Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 17/20 | 0.69 |
| ▸ | ESR1 | P03372 | 6/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478613 | 1.00 | ESR2 (0.69) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10762155 | 0.94 | ESR2 (0.62) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10894056 | 0.94 | ESR2 (0.62) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10762150 | 0.94 | ESR2 (0.62) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL18257846 | 0.93 | ESR2 (0.73) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL18257844 | 0.93 | ESR2 (0.73) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11187444 | 0.89 | ESR2 (0.52) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11187439 | 0.89 | ESR2 (0.52) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL1119887 | 0.85 | ESR2 (0.71) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL1531852 | 0.85 | ESR2 (0.71) | ESR2ESR1CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656334-B | Phenolic oligomer, preparation method thereof and asphaltene deposition inhibitor composition | 中国石油化工股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-114763469-B | Oil-soluble paraffin removal and prevention agent and preparation method thereof | 中国石油化工股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| EP-3071541-B1 | SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM | UNIV MARQUETTE (US) | 2023-06-07 | — | — | EP | disclosed |
| CN-114763469-A | Oil-soluble paraffin removal and prevention agent and preparation method thereof | 中国石油化工股份有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-114656334-A | Phenolic aldehyde oligomer, preparation method thereof and asphaltene deposition inhibitor composition | 中国石油化工股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| US-10570077-B2 | Substituted (4'-hydroxyphenyl)cyclohexane compounds and uses thereof as selective agonists of the estrogen receptor beta isoform | MARQUETTE UNIVERSITY (US) | 2020-02-25 | — | — | US | disclosed |
| US-9599760-B2 | Composition for optical film, and films and display device | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-03-21 | — | — | US | disclosed |
| US-20160340279-A1 | SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOAKLKANE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM | MARQUETTE UNIVERSITY (US) | 2016-11-24 | — | — | US | disclosed |
| US-20160187552-A1 | COMPOSITION FOR OPTICAL FILM, AND FILMS AND DISPLAY DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-06-30 | — | — | US | disclosed |
| US-5830976-A | POLYAMIC ACID FROM BIPHENYLTETRACARBOXYLIC ACID AND (CYCLOHEXYLPHENOXY)ALKYL 3,5-DIAMINOBENZOATE, LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| WO-1995010498-A1 | 3,4,5-TRIFLUOROBENZENES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1995-04-20 | — | — | WO | disclosed |
| US-5324449-A | Substituted phenyl trifluoromethyl ethers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-28 | — | — | US | disclosed |
| US-5230827-A | DERIVATIVES OF 2,3-DIFLUOROBENZOIC ACID | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-27 | — | — | US | disclosed |
| EP-0334911-B1 | SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS | MERCK PATENT GmbH (DE) | 1993-02-10 | — | — | EP | disclosed |
| EP-0358741-B1 | DERIVATIVES OF 2,3-DIFLUOROBENZOIC ACID | MERCK PATENT GmbH (DE) | 1993-02-10 | — | — | EP | disclosed |
| EP-0358741-A1 | DERIVATIVES OF 2,3-DIFLUOROBENZOIC ACID. | MERCK PATENT GMBH (DE) | 1990-03-21 | — | — | EP | disclosed |
| EP-0334911-A1 | SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS | MERCK PATENT GmbH (DE) | 1989-10-04 | — | — | EP | disclosed |
| WO-1989008688-A1 | DERIVATIVES OF 2,3-DIFLUOROBENZOIC ACID | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989002884-A1 | SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340279-A1 | SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOAKLKANE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM | ESR2, GPER1, ESRRG | ESR2 1/4885ESR1 4/4885CYP2C9 1298/4885 |
| US-10570077-B2 | Substituted (4'-hydroxyphenyl)cyclohexane compounds and uses thereof as selective agonists of the estrogen receptor beta isoform | ESR2, GPER1, ESR1 | ESR2 1/4885ESR1 3/4885CYP2C9 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.