Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 10/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763471 | 1.00 | LMNA (0.56) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10764798 | 0.85 | PTGS1 (0.56) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10764792 | 0.85 | PTGS1 (0.56) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10762149 | 0.81 | LMNA (0.55) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10762154 | 0.81 | LMNA (0.55) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10761014 | 0.79 | LMNA (0.68) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10761020 | 0.79 | LMNA (0.68) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10760655 | 0.78 | LMNA (0.52) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10762601 | 0.78 | LMNA (0.52) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL10762603 | 0.78 | LMNA (0.52) | LMNAKDM4ECYP1A2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |