Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16157109 | 0.72 | NPC1 (0.67) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6777717 | 0.71 | POLB (0.59) | POLBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL23539603 | 0.70 | BRD4 (0.55) | IMPDH2AAK1MAPK1TDP1MAPT | |
| SCHEMBL9955245 | 0.70 | PDK2 (0.48) | ADRA1AIMPDH2AAK1PDK2ADRA1D | |
| SCHEMBL28015046 | 0.70 | ATR (0.49) | POLBNPC1RAB9AALDH1A1ADRA1A | |
| SCHEMBL38656167 | 0.70 | PDK2 (0.48) | ADRA1AIMPDH2AAK1PDK2ADRA1D | |
| SCHEMBL4355515 | 0.69 | POLB (0.44) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27976182 | 0.68 | AKR1B1 (0.44) | NPC1RAB9AALDH1A1ADRA1AIMPDH2 | |
| SCHEMBL26259988 | 0.67 | MEN1 (0.48) | ADRA1AIMPDH2PDK2ADRA1DADRA1B | |
| SCHEMBL26259975 | 0.67 | CYP11B1 (0.48) | ADRA1AIMPDH2PDK2ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083975-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
| US-4602940-A | HERBICIDES, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-07-29 | — | — | US | disclosed |
| US-4534790-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| US-4465505-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0083975-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |