Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203340 | 0.81 | ALDH1A1 (0.47) | HTTHSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8631968 | 0.78 | POLB (0.42) | POLBHTTHSD17B10EGFRRAB9A | |
| SCHEMBL6777717 | 0.70 | POLB (0.59) | POLBHSD17B10EGFRRAB9ASMN1; SMN2 | |
| SCHEMBL10763514 | 0.69 | POLB (0.45) | POLBHTTHSD17B10EGFRRAB9A | |
| SCHEMBL8628193 | 0.69 | POLB (0.41) | POLBHTTHSD17B10EGFRRAB9A | |
| SCHEMBL17626796 | 0.68 | POLB (0.44) | POLBHTTHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL8626370 | 0.67 | CRBN (0.41) | HSD17B10RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL3175492 | 0.67 | HPGD (0.44) | HTTHSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9034353 | 0.67 | POLB (0.42) | POLBHTTHSD17B10EGFRRAB9A | |
| SCHEMBL570014 | 0.66 | CHRNB4 (0.42) | RAB9ASMN1; SMN2NPC1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072512-A1 | Herbicide compounds based on N-Azinyl-N'-pyridylsulfonyl-ureas | Bayer CropScience AG (DE) | 2009-06-24 | — | — | EP | disclosed |