Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11658969 | 0.81 | BRD4 (0.57) | BRD4SRD5A1PDE4APDE4BPDE4C | |
| SCHEMBL6772965 | 0.80 | BRD4 (0.68) | BRD4ADRA1DADRA1AADRA1BSRD5A1 | |
| SCHEMBL6556310 | 0.75 | BRD4 (1.00) | BRD4SRD5A1PDE4APDE4BPDE4C | |
| SCHEMBL15203831 | 0.75 | BRD4 (1.00) | BRD4SRD5A1PDE4APDE4BPDE4C | |
| SCHEMBL8406210 | 0.75 | BRD4 (1.00) | BRD4SRD5A1PDE4APDE4BPDE4C | |
| SCHEMBL24877638 | 0.74 | TP53 (0.48) | TP53RECQLHTR6ADRA1DADRA1A | |
| SCHEMBL31444506 | 0.73 | GSK3B (0.42) | BRD4TP53RECQLSRD5A1DPP4 | |
| SCHEMBL11083189 | 0.73 | ADRA1A (0.40) | BRD4TP53RECQLHTR6ADRA1D | |
| SCHEMBL427764 | 0.72 | TP53 (0.85) | TP53RECQLHTR6ADRA1DADRA1A | |
| SCHEMBL2459716 | 0.72 | BRD4 (0.57) | BRD4ADRA1DADRA1AADRA1BSRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699918-A | ANTICOAGULANTS, ANTIARRHYTHMIA AGENTS | LABORATOIRES JACQUES LOGEAIS (FR) | 1987-10-13 | — | — | US | disclosed |
| US-4556674-A | ANTICOAGULANTS, ANTIARRHYTHMIA AGENTS | LABORATOIRES JACQUES LOGEAIS (FR) | 1985-12-03 | — | — | US | disclosed |