Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 8/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763204 | 0.85 | PDE3B (0.51) | PDE3APDE3BPTGS1PIM1PIM2 | |
| SCHEMBL10761737 | 0.83 | PDE3B (0.67) | PDE3APDE3BPBRM1CYP3A4CYP2D6 | |
| SCHEMBL10765163 | 0.82 | PDE3B (0.65) | PDE3APDE3BAHRPBRM1PDE4B | |
| SCHEMBL10761194 | 0.82 | PDE3B (0.65) | PDE3APDE3BPBRM1PDE4B | |
| SCHEMBL10759796 | 0.82 | PDE3B (0.69) | PDE3APDE3BPBRM1PDE4B | |
| SCHEMBL7285568 | 0.82 | PDE3B (0.65) | PDE3APDE3BPBRM1PDE4B | |
| SCHEMBL10760728 | 0.80 | PDE3B (0.73) | PDE3APDE3BPBRM1CYP3A4CYP1A2 | |
| SCHEMBL10767384 | 0.80 | PDE3B (0.62) | PDE3APDE3BPTGS1 | |
| SCHEMBL10761240 | 0.80 | PDE3B (0.62) | PDE3APDE3BPBRM1CYP1A2PDE4B | |
| SCHEMBL10760276 | 0.79 | PDE3B (0.61) | PDE3APDE3BPBRM1PTGS1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |