Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253861 | 0.80 | CYP3A4 (0.43) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30183188 | 0.74 | SMN1; SMN2 (0.51) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10757760 | 0.73 | CYP3A4 (0.55) | KMT2ANOTUMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10762515 | 0.73 | NOTUM (0.47) | KMT2ANOTUMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4328936 | 0.69 | MEN1 (0.75) | KMT2AMEN1CYP19A1 | |
| SCHEMBL11627293 | 0.69 | CYP19A1 (0.72) | KMT2AMEN1CYP3A4CYP19A1 | |
| SCHEMBL24783686 | 0.69 | CYP1A2 (0.50) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26402 | 0.69 | MEN1 (1.00) | KMT2AMEN1CYP19A1SMN1; SMN2 | |
| SCHEMBL8815628 | 0.69 | GAA (0.50) | KMT2ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11955039 | 0.68 | LOXL2 (0.43) | KMT2ACYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661603-A | ENZYME INHIBITORS; VASODILATORS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0110996-B1 | IMIDAZOLE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-09-03 | — | — | EP | disclosed |
| US-4581369-A | THROMBANE INHIBITORS, ANTICOAGULANTS, VASODILATORS, AND TREATMENT OF LIVER DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-04-08 | — | — | US | disclosed |
| EP-0110996-A1 | IMIDAZOLE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-06-20 | — | — | EP | disclosed |