Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19028056 | 0.82 | ALDH1A1 (0.44) | DPP4ALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL30562670 | 0.82 | ALDH1A1 (0.44) | DPP4ALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL10586185 | 0.81 | KMT2A (0.46) | DPP4ALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL24683112 | 0.80 | CA12 (0.40) | ALDH1A1MAPK1KMT2AMEN1KDM4E | |
| SCHEMBL31574400 | 0.80 | DPP4 (0.52) | DPP4ALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL10766033 | 0.80 | DPP4 (0.42) | DPP4ALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL28149481 | 0.79 | KMT2A (0.43) | DPP4ALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL10760359 | 0.78 | DPP4 (0.41) | DPP4ALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL10760271 | 0.78 | ALDH1A1 (0.58) | DPP4ALDH1A1KMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL11547616 | 0.78 | KMT2A (0.42) | DPP4ALDH1A1MAPK1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225172-A1 | Process for the preparation of 5-chloro and 5-bromo-2-hydroxynicotinicacids | A.H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-10 | — | — | EP | disclosed |