Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15303566 | 0.90 | TSHR (0.41) | TSHRGRIK1HPGDCYP3A4TDP1 | |
| SCHEMBL7549068 | 0.84 | TSHR (0.50) | TSHRALDH1A1GRIK1HPGDEP300 | |
| SCHEMBL9149500 | 0.80 | TSHR (0.49) | TSHRALDH1A1GRIK1HPGDEP300 | |
| SCHEMBL8971288 | 0.80 | TSHR (0.49) | TSHRALDH1A1GRIK1HPGDEP300 | |
| SCHEMBL10647880 | 0.78 | TSHR (0.44) | TSHRALDH1A1CYP3A4FAAH | |
| SCHEMBL4791450 | 0.78 | GRIK1 (0.53) | TSHRALDH1A1GRIK1EP300FAAH | |
| SCHEMBL211113 | 0.78 | CYP3A4 (0.39) | TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL10901744 | 0.77 | TSHR (0.39) | TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL325189 | 0.75 | TSHR (0.51) | TSHRALDH1A1HPGDEP300FAAH | |
| SCHEMBL8690100 | 0.75 | TSHR (0.51) | TSHRALDH1A1HPGDEP300FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122788-B1 | SELF-LEVELING POLISH COMPOSITIONS AND POLYMER COMPOSITIONS USEFUL THEREIN | ROHM AND HAAS COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| EP-0122788-A2 | Self-leveling polish compositions and polymer compositions useful therein | ROHM AND HAAS COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |
| US-4460734-A | ETHYLENE OXIDE FATTY ALCOHOL ADDUCT, ADDITION POLYMER | ROHM AND HAAS COMPANY (US) | 1984-07-17 | — | — | US | disclosed |