SCHEMBL10901744

SCHEMBL10901744

C=CCOC(=O)C(=CC)CC=C

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 2/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
PTP4A3 O75365 2/20 0.30
PTP4A1 Q93096 2/20 0.30
NPSR1 Q6W5P4 1/20 0.30
PTP4A2 Q12974 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10997210 0.83 NPSR1 (0.41) TSHRMAPTALDH1A1HSD17B10MEN1
SCHEMBL481459 0.82 MAPT (0.38) TSHRCYP3A4TDP1MAPTCACNA1B
Ammonia Solution, Strong SCHEMBL11223968 0.82 CYP3A4 (0.36) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL2936820 0.80 MAPT (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL3902728 0.80 CYP3A4 (0.35) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL2938493 0.80 MAPT (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL2936821 0.80 MAPT (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL211113 0.80 CYP3A4 (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL15303566 0.80 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL11284522 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110922952-A High-temperature high-salinity reservoir polymer microsphere profile control and flooding agent and preparation method and application thereof 成都新驱势石油技术开发有限公司 2020-03-27 CN disclosed
US-4582635-A SUSTAINED RELEASE TAKASAGO PERFUMERY CO., LTD. (JP) 1986-04-15 US disclosed
US-3931373-A Replication processes for producing plastic optical components J. O. BEATTIE RESEARCH COMPANY (US) 1976-01-06 US disclosed