Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.45 |
| ▸ | CCR9 | P51686 | 18/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1036740 | 0.91 | HSD17B2 (0.45) | HSD17B2CCR9 | |
| SCHEMBL1038561 | 0.89 | HSD17B2 (0.44) | HSD17B2CCR9 | |
| SCHEMBL1034935 | 0.88 | CCR9 (0.45) | HSD17B2CCR9 | |
| SCHEMBL1076570 | 0.87 | HSD17B2 (0.43) | HSD17B2CCR9 | |
| SCHEMBL1035106 | 0.86 | HSD17B2 (0.47) | HSD17B2CCR9 | |
| SCHEMBL1034964 | 0.86 | HSD17B2 (0.46) | HSD17B2CCR9 | |
| SCHEMBL1035070 | 0.85 | HSD17B2 (0.47) | HSD17B2CCR9 | |
| SCHEMBL1039060 | 0.85 | HSD17B2 (0.51) | HSD17B2CCR9 | |
| SCHEMBL1040059 | 0.83 | CCR2 (0.49) | — | |
| SCHEMBL1033990 | 0.81 | CCR9 (0.48) | HSD17B2CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049515-B1 | TRIAZOLYL PYRIDYL BENZENESULFONAMIDES AS CCR2 OR CCR9 MODULATORS FOR THE TREATMENT OF ATHEROSCLEROSIS | CHEMOCENTRYX INC (US) | 2011-01-26 | — | — | EP | disclosed |