SCHEMBL10766331

SCHEMBL10766331

Cc1cc(Br)c(OCOc2c(Br)cc(C)cc2Br)c(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
KDM4E B2RXH2 7/20 0.41
MAPT P10636 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
ALDH1A1 P00352 6/20 0.40
LMNA P02545 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
THRB P10828 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
THRA P10827 1/20 0.37
HRH3 Q9Y5N1 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25402814 0.89 KMT2A (0.46) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL25925324 0.80 KMT2A (0.48) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL7266985 0.79 KMT2A (0.46) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL11451272 0.79 TSHR (0.39) KMT2AMEN1MAPTL3MBTL1ALDH1A1
SCHEMBL12772147 0.79 MAPT (0.53) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL14681886 0.78 KMT2A (0.53) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL7636855 0.78 KMT2A (0.49) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL7180070 0.78 KDM4E (0.48) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL12833107 0.78 THRA (0.57) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL31716556 0.76 KMT2A (0.38) KMT2AMEN1KDM4EMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0236848-A1 Bis- or poly-(bromo-4-methyl-phenoxy)-alkanes and -alkenes, process for preparing same and use thereof as uv-stable fireprotective agents for synthetic materials Chemische Fabrik Kalk GmbH (DE) 1987-09-16 EP disclosed