Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10769280 | 0.99 | HPGD (0.49) | HPGDTSHRHSD17B10USP2LMNA | |
| SCHEMBL10767338 | 0.86 | NPSR1 (0.53) | HPGDTSHRHSD17B10LMNAHTT | |
| SCHEMBL10767996 | 0.86 | NPC1 (0.45) | HPGDHSD17B10USP2HTTNPC1 | |
| SCHEMBL10768758 | 0.86 | HRH4 (0.51) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5306360 | 0.81 | NPC1 (0.47) | TSHRHSD17B10LMNAHTTNPC1 | |
| SCHEMBL10768750 | 0.80 | DPP4 (0.55) | TSHRKMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL10769575 | 0.77 | MAPT (0.56) | HPGDTSHRHSD17B10USP2LMNA | |
| SCHEMBL17232700 | 0.74 | NPC1 (0.58) | TSHRHSD17B10HTTNPC1RAB9A | |
| SCHEMBL26373822 | 0.74 | ALDH1A1 (0.53) | HSD17B10HTTNPC1RAB9AKMT2A | |
| SCHEMBL10532301 | 0.73 | NPC1 (0.55) | HPGDTSHRHSD17B10USP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225522-A1 | Imidazopyridazine alkene carboxamides, process for their preparation, intermediate products and their preparation | BAYER AG (DE) | 1987-06-16 | — | — | EP | disclosed |