SCHEMBL10766890

SCHEMBL10766890

C=C/C=C/CCC=C.C=C/C=C/CCC=C.[Ni]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4804750 1.00 TSHR (0.33) TSHRALDH1A1
SCHEMBL8564227 0.97
SCHEMBL138124 0.97
SCHEMBL138123 0.97
SCHEMBL9475809 0.87 LSS (0.31)
SCHEMBL9179964 0.85 TSHR (0.32) TSHR
SCHEMBL28730944 0.79
SCHEMBL5610514 0.79
SCHEMBL1114072 0.79
SCHEMBL1288145 0.79 TSHR (0.43) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0128596-B1 ETHYLENE OLIGOMERIZATION PROCESS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-05-20 EP disclosed
US-4503280-A NICKEL COMPLEX CATALYST SHELL OIL COMPANY (US) 1985-03-05 US disclosed
EP-0128596-A2 Ethylene oligomerization process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-12-19 EP disclosed
US-4472525-A POLYMERIZATION CATALYST CONSISTING OF NICKEL COMPOUND AND O-DIHYDROCARBYLPHOSPHINOPHENYL ALCOHOL ETHER SHELL OIL COMPANY (US) 1984-09-18 US disclosed
EP-0014239-A2 Preparation of tertiary 2-carboxyethyl- and carboxymethyl phosphines, their salts and their use CHEMISCHE WERKE HÜLS AG (DE) 1980-08-20 EP disclosed