SCHEMBL4804750

SCHEMBL4804750

C=CC=CCCC=C.C=CC=CCCC=C.[Ni]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10766890 1.00 TSHR (0.33) TSHRALDH1A1
SCHEMBL8564227 0.97
SCHEMBL138124 0.97
SCHEMBL138123 0.97
SCHEMBL9475809 0.87 LSS (0.31)
SCHEMBL9179964 0.85 TSHR (0.32) TSHR
SCHEMBL28730944 0.79
SCHEMBL5610514 0.79
SCHEMBL1114072 0.79
SCHEMBL1288145 0.79 TSHR (0.43) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6818714-B1 CATALYTIC SYSTEM USING NEW LIGANDS WHICH, USED IN SITU WITH NICKEL COMPLEX IN ZERO OXIDATION STATE, MAKE IT POSSIBLE TO OBTAIN POLYOLEFIN WITH VERY HIGH ACTIVITY EVEN IN PRESENCE OF POLAR MEDIUM ATOFINA (FR) 2004-11-16 US claimed
EP-1165577-B1 METHOD FOR POLYMERISING OLEFINS IN THE PRESENCE OF NICKEL COMPLEXES AND CORRESPONDING CATALYTIC SYSTEM ATOFINA (FR) 2004-06-16 EP claimed
JP-2002540225-A 2002-11-26 JP claimed
EP-1165577-A1 METHOD FOR POLYMERISING OLEFINS IN THE PRESENCE OF NICKEL COMPLEXES AND CORRESPONDING CATALYTIC SYSTEM Atofina (FR) 2002-01-02 EP claimed
WO-2000056744-A1 METHOD FOR POLYMERISING OLEFINS IN THE PRESENCE OF NICKEL COMPLEXES AND CORRESPONDING CATALYTIC SYSTEM ATOFINA (FR) 2000-09-28 WO claimed
US-7378474-B2 Olefin polymerization catalyst KANEKA CORPORATION (JP) 2008-05-27 US disclosed
US-20070244261-A1 Polyolefin Graft Copolymer, Composition and Method for Producing Same KANEKA CORPORATION (JP) 2007-10-18 US disclosed
US-20070167316-A1 Olefin polymerization catalyst KANEKA CORPORATION 2007-07-19 US disclosed
EP-1762579-A1 POLYOLEFIN GRAFT COPOLYMER, COMPOSITION AND METHOD FOR PRODUCING SAME Kaneka Corporation (JP) 2007-03-14 EP disclosed
EP-1719782-A1 OLEFIN POLYMERIZATION CATALYST KANEKA CORPORATION (JP) 2006-11-08 EP disclosed
US-6818714-B1 CATALYTIC SYSTEM USING NEW LIGANDS WHICH, USED IN SITU WITH NICKEL COMPLEX IN ZERO OXIDATION STATE, MAKE IT POSSIBLE TO OBTAIN POLYOLEFIN WITH VERY HIGH ACTIVITY EVEN IN PRESENCE OF POLAR MEDIUM ATOFINA (FR) 2004-11-16 US disclosed
EP-1165577-B1 METHOD FOR POLYMERISING OLEFINS IN THE PRESENCE OF NICKEL COMPLEXES AND CORRESPONDING CATALYTIC SYSTEM ATOFINA (FR) 2004-06-16 EP disclosed
EP-0128596-B1 ETHYLENE OLIGOMERIZATION PROCESS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-05-20 EP disclosed
US-4503280-A NICKEL COMPLEX CATALYST SHELL OIL COMPANY (US) 1985-03-05 US disclosed
EP-0128596-A2 Ethylene oligomerization process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-12-19 EP disclosed
US-4472525-A POLYMERIZATION CATALYST CONSISTING OF NICKEL COMPOUND AND O-DIHYDROCARBYLPHOSPHINOPHENYL ALCOHOL ETHER SHELL OIL COMPANY (US) 1984-09-18 US disclosed
US-4328163-A Process for the preparation of secondary and tertiary 2-carboxyethyl- and carboxymethylphosphines and their salts, as well as the use thereof CHEMISCHE WERKE HUELS, A.G. (DE) 1982-05-04 US disclosed
US-4315867-A NICKEL CONTAINING CATALYST CHEMISCHE WERKE HUELS, AKTIENGESELLSCHAFT (DE) 1982-02-16 US disclosed
EP-0014747-A1 Secondary and tertiary 2-carboxyethyl and carboxymethyl phosphines and their salts, process for their preparation and their use CHEMISCHE WERKE HÜLS AG (DE) 1980-09-03 EP disclosed
EP-0014239-A2 Preparation of tertiary 2-carboxyethyl- and carboxymethyl phosphines, their salts and their use CHEMISCHE WERKE HÜLS AG (DE) 1980-08-20 EP disclosed