Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | GOT1 | P17174 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 2/20 | 0.56 |
| ▸ | CCND1 | P24385 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | AANAT | Q16613 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456819 | 0.86 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL3456815 | 0.86 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL349371 | 0.86 | KMT2A (0.76) | KMT2AMEN1GOT1TSHRMAPT | |
| SCHEMBL8525238 | 0.81 | MEN1 (0.57) | KMT2AMEN1LMNATSHRBLM | |
| SCHEMBL5281197 | 0.81 | MEN1 (0.57) | KMT2AMEN1LMNATSHRBLM | |
| SCHEMBL29581685 | 0.79 | KDM4E (0.65) | KMT2AMEN1LMNATSHRBLM | |
| SCHEMBL21641800 | 0.79 | KDM4E (0.65) | KMT2AMEN1LMNATSHRBLM | |
| SCHEMBL21641799 | 0.79 | KDM4E (0.65) | KMT2AMEN1LMNATSHRBLM | |
| SCHEMBL627038 | 0.78 | MEN1 (0.74) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL31285794 | 0.78 | KDM4E (0.60) | KMT2AMEN1LMNATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275433-B1 | METASTIN DERIVATIVE AND USE THEREOF | UNIV KYOTO (JP) | 2017-06-07 | — | — | EP | disclosed |
| US-8592379-B2 | Metastin derivative and use thereof | KYOTO UNIVERSITY (JP) | 2013-11-26 | — | — | US | disclosed |
| US-20110039786-A1 | METASTIN DERIVATIVE AND USE THEREOF | KYOTO UNIVERSITY (JP) | 2011-02-17 | — | — | US | disclosed |
| EP-2275433-A1 | METASTIN DERIVATIVE AND USE THEREOF | Kyoto University (JP) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009139298-A1 | METASTIN DERIVATIVE AND USE THEREOF | 国立大学法人京都大学 (JP) | 2009-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039786-A1 | METASTIN DERIVATIVE AND USE THEREOF | MEN1, HGF, STMN1 | KMT2A 2963/4885MEN1 1/4885GOT1 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.