HGF — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL2868047	0.91	4/20
SCHEMBL2855807	0.78	4/20
SCHEMBL3913563	0.72	4/20
SCHEMBL3112398	0.52	4/20
SCHEMBL3101384	0.48	4/20
SCHEMBL2868963	1.00	3/20
SCHEMBL2868521	0.91	3/20
SCHEMBL2863129	0.90	3/20
SCHEMBL2869076	0.90	3/20
SCHEMBL1565046	0.90	3/20
SCHEMBL2861831	0.88	3/20
SCHEMBL2856661	0.82	3/20
SCHEMBL2861730	0.81	3/20
SCHEMBL2861036	0.80	3/20
SCHEMBL2862063	0.80	3/20
SCHEMBL2863100	0.80	3/20
SCHEMBL3913569	0.79	3/20
SCHEMBL3920694	0.78	3/20
SCHEMBL2854153	0.77	3/20
SCHEMBL3917599	0.74	3/20

Clinical trials — most relevant to HGF by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Evaluation of Platelet Rich Fibrin Matrix as Regenerative Material in Intraosseous Defects	PHASE3	COMPLETED
Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic Failure	PHASE1/PHASE2	UNKNOWN
Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia	PHASE2	COMPLETED
Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain Syndrome	PHASE1/PHASE2	COMPLETED
The Effectiveness of Allogenic Mesenchymal Stem Cells Therapy on Hair Regrowth in Androgenetic Alopecia.	PHASE1/PHASE2	ENROLLING_BY_INVITATION
Sunitinib for Advanced Thymus Cancer Following Earlier Treatment	PHASE2	COMPLETED
Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia	PHASE2	COMPLETED
Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia Patients With Peripheral Ischemic Ulcers	PHASE2	COMPLETED
The Safety and Tolerability of Engensis (VM202) in Patients With Charcot-Marie-Tooth Disease Subtype 1A (CMT1A)	PHASE1/PHASE2	COMPLETED
Stem Cell Treatment for Lung Injury Caused by Major Infectious Diseases	PHASE1/PHASE2	UNKNOWN
Intranasal Inhalations of M2 Macrophage Soluble Factors in Children With Developmental Speech Disorders	PHASE1/PHASE2	COMPLETED
Pazopanib and ARQ 197 for Advanced Solid Tumors	PHASE1	COMPLETED
A Phase 1 Dose-Escalation Study in Advanced Solid Tumors, Lymphomas or Multiple Myeloma	PHASE1	COMPLETED
Baker Cyst Aspiration Combined With Platelet-rich Plasma Injection in Knee Osteoarthritis	nan	COMPLETED
Hyperbaric Oxygen Therapy in Patients With Chronic Stable Ischemic Heart Disease: An Option for Therapeutic Angiogenesis?	nan	UNKNOWN
Finger-prick Autologous Blood (FAB) for Use in Dry Mouth	nan	UNKNOWN
Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response	nan	COMPLETED
Subtenon PRP Injection for Geographic Atrophy in Dry Age-Related Macular Degeneration	nan	COMPLETED
Evaluation of the Use of Granulocyte Colony Stimulating Factor (GCSF) in Post Kasai Type 3 Biliary Atresia	nan	RECRUITING
Pulmonary and Systemic Hepatocyte Growth Factors in Patients With COPD	nan	COMPLETED
Growth Factors and Hepatic Progenitor Cells in Acute Liver Failure	nan	UNKNOWN
Therapeutic Irrigation Procedures to Treat Apical Periodontitis	nan	COMPLETED
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Serum Retinoic Acid Induced Protein 14 (RAI14) and Metastasis Associated Cancer Colon -1 (MACC-1) in Breast Cancer	nan	UNKNOWN
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-BI-201 Clinical Trial	nan	COMPLETED
Platelet Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome (HiPPO Trial)	nan	COMPLETED
Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia: A Systematic Review and Meta-analysis	nan	UNKNOWN
Stromal Vascular Cells for the Treatment of Diabetic Peripheral Neuropathy	nan	COMPLETED
Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study	nan	NOT_YET_RECRUITING
Evaluation of Risk of hEpatocellular Carcinoma	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a HGF binder may also engage these)

Protein	Name	Similarity
P17945	—	1.000	P17945 →
Q08048	—	1.000	Q08048 →
Q867B7	—	1.000	Q867B7 →
Q76BS1	—	1.000	Q76BS1 →
Q9BH09	—	0.998	Q9BH09 →
P19637	—	0.997	P19637 →
P11214	—	0.996	P11214 →
P29598	—	0.996	P29598 →
PLG	Plasminogen	0.996	landscape →
Q5R8X6	—	0.995	Q5R8X6 →
P26262	—	0.995	P26262 →
Q29485	—	0.995	Q29485 →
O18783	—	0.995	O18783 →
P49150	—	0.994	P49150 →
P04185	—	0.994	P04185 →
P20918	—	0.993	P20918 →
B4F6N6	—	0.993	B4F6N6 →
Q5E9Z2	—	0.993	Q5E9Z2 →
Q2KJ63	—	0.993	Q2KJ63 →
Q8SQ23	—	0.993	Q8SQ23 →
Q5R8J0	—	0.992	Q5R8J0 →
Q8MHY7	—	0.992	Q8MHY7 →
P12545	—	0.992	P12545 →
P19221	—	0.992	P19221 →
P98119	—	0.992	P98119 →
P97435	—	0.992	P97435 →
P33587	—	0.991	P33587 →
P31394	—	0.991	P31394 →
Q58L93	—	0.991	Q58L93 →
Q05589	—	0.991	Q05589 →