Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.32 |
| ▸ | TERT | O14746 | 3/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765459 | 1.00 | ALOX5 (0.33) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10916091 | 1.00 | ALOX5 (0.33) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10359551 | 0.95 | ALOX5 (0.39) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10914511 | 0.95 | ALOX5 (0.39) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10359581 | 0.95 | ALOX5 (0.39) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10914507 | 0.95 | ALOX5 (0.39) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10359592 | 0.91 | EPHX2 (0.34) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10359333 | 0.91 | EPHX2 (0.34) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10359750 | 0.91 | EPHX2 (0.34) | ALOX5EPHX2TERTPTPN1PPARG | |
| SCHEMBL10766548 | 0.91 | EPHX2 (0.34) | ALOX5EPHX2TERTPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-A1 | Cyclohexanealkanoic acids | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4622422-A | FOR TREATMENT OF BRONCHIAL ASTHMA | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-11 | — | — | US | disclosed |