Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12851338 | 0.86 | KCNA5 (0.51) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL10761796 | 0.82 | MAOA (0.39) | MTNR1AMTNR1BF10MAOAMAOB | |
| SCHEMBL28381160 | 0.78 | F10 (0.50) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL16562186 | 0.78 | MAOA (0.47) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6097066 | 0.77 | F10 (0.64) | MTNR1AMTNR1BF10MAOAMAOB | |
| SCHEMBL27951203 | 0.77 | F10 (0.64) | MTNR1AMTNR1BF10MAOAMAOB | |
| SCHEMBL15472878 | 0.76 | MAOB (0.71) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL2830090 | 0.76 | MAOB (0.71) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL9805030 | 0.76 | ADORA2A (0.41) | MAOAMAOBLMNAADRB1 | |
| SCHEMBL20448471 | 0.74 | MAOA (0.45) | MTNR1AF10MAOAMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705799-A | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0184170-A2 | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-06-11 | — | — | EP | disclosed |
| EP-0127902-A2 | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |