SCHEMBL10768166

SCHEMBL10768166

C/C=C/CC/C=C/C(=O)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.39
CNR1 P21554 6/20 0.39
TRPA1 O75762 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
PPARG P37231 2/20 0.37
PPARD Q03181 2/20 0.37
PPARA Q07869 2/20 0.37
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10768168 1.00 CNR2 (0.39) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL14764867 0.85 PPARA (0.49) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL14764866 0.85 PPARA (0.49) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL16117665 0.79 TAS1R3 (0.42) CNR2CNR1PPARGPPARAALDH1A1
SCHEMBL16117663 0.79 CA1 (0.48) CNR2CNR1KDM4EALDH1A1MAPT
SCHEMBL23178982 0.77 GABRR1 (0.31) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL21123003 0.77 KMT2A (0.30)
SCHEMBL2868540 0.75
SCHEMBL8084069 0.75
SCHEMBL2617046 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231896-A1 Alpha, beta-unsaturated ketones and their use as aroma chemicals KURARAY CO., LTD. (JP) 1987-08-12 EP disclosed