Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.63 |
| ▸ | APEX1 | P27695 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627537 | 0.94 | ENPP2 (0.63) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL2028368 | 0.94 | ENPP2 (0.63) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL12810338 | 0.92 | APEX1 (0.61) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL16062713 | 0.89 | ENPP2 (0.62) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL16062720 | 0.89 | ENPP2 (0.62) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL10380130 | 0.88 | ENPP2 (0.78) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL15153907 | 0.88 | ENPP2 (0.78) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL8819426 | 0.88 | ENPP2 (0.78) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL16062714 | 0.87 | ENPP2 (0.60) | ENPP2APEX1CYP1A2PRMT1CYP2C9 | |
| SCHEMBL11758267 | 0.87 | APEX1 (0.77) | ENPP2APEX1CYP1A2PRMT1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225730-A2 | Reactive Dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-16 | — | — | EP | disclosed |