Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10767985 | 0.88 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL26241675 | 0.69 | KMT2A (0.58) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL10405746 | 0.68 | CYSLTR2 (0.52) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL10405745 | 0.68 | CYSLTR2 (0.52) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL10403173 | 0.68 | CYSLTR2 (0.58) | MEN1KMT2ANPC1ALDH1A1MAPK1 | |
| SCHEMBL10403172 | 0.68 | CYSLTR2 (0.58) | MEN1KMT2ANPC1ALDH1A1MAPK1 | |
| SCHEMBL10401709 | 0.68 | CYSLTR2 (0.80) | ALDH1A1SMN1; SMN2KDM4ECYSLTR2CYSLTR1 | |
| SCHEMBL10401708 | 0.68 | CYSLTR2 (0.80) | ALDH1A1SMN1; SMN2KDM4ECYSLTR2CYSLTR1 | |
| SCHEMBL28514110 | 0.67 | KMT2A (0.43) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| Butyric Acid SCHEMBL10769260 | 0.67 | CYSLTR1 (0.50) | MEN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219308-A2 | 2-Substituted quinolines | MERCK FROSST CANADA INC. (CA) | 1987-04-22 | — | — | EP | disclosed |