Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 18/20 | 0.58 |
| ▸ | MEN1 | O00255 | 17/20 | 0.58 |
| ▸ | NPC1 | O15118 | 14/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 12/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282407 | 0.77 | AGTR1 (0.60) | KMT2AMEN1NPC1AGTR1RAB9A | |
| SCHEMBL16971024 | 0.74 | KMT2A (1.00) | KMT2AMEN1NPC1AGTR1HSP90AA1 | |
| SCHEMBL16971022 | 0.74 | KMT2A (1.00) | KMT2AMEN1NPC1AGTR1HSP90AA1 | |
| SCHEMBL10767985 | 0.73 | MEN1 (0.54) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL27952547 | 0.70 | KMT2A (0.58) | KMT2AMEN1NPC1AGTR1RAB9A | |
| SCHEMBL12281112 | 0.70 | KMT2A (0.60) | KMT2AMEN1NPC1AGTR1RAB9A | |
| SCHEMBL9799609 | 0.70 | ELANE (0.46) | KMT2AMEN1MAPTNPSR1HTT | |
| SCHEMBL578720 | 0.70 | ELANE (0.46) | KMT2AMEN1MAPTNPSR1HTT | |
| SCHEMBL15547750 | 0.69 | KMT2A (0.43) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10769266 | 0.69 | MEN1 (0.47) | KMT2AMEN1NPC1AGTR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | SIERRA SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | SIERRA SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | TERT, TERF2, RNGTT | KMT2A 280/4885MEN1 3550/4885NPC1 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.