⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydantoin SCHEMBL27705088 | 0.97 | CRBN (0.52) | — | |
| Hydantoin SCHEMBL27690 | 0.97 | — | — | |
| Hydantoin SCHEMBL7285865 | 0.97 | — | — | |
| Hydantoin SCHEMBL3479397 | 0.94 | — | — | |
| Hydantoin SCHEMBL753774 | 0.94 | — | — | |
| Hydantoin SCHEMBL3246334 | 0.94 | — | — | |
| Hydantoin SCHEMBL8639680 | 0.94 | — | — | |
| Hydantoin SCHEMBL10578141 | 0.94 | — | — | |
| Hydantoin SCHEMBL1786052 | 0.94 | — | — | |
| Hydantoin SCHEMBL2224461 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668686-A | 1,3-DIHYDRO-2H-IMIDAZO/4,5-B/QUINOLINE-2-ONES | BRISTOL-MYERS COMPANY (US) | 1987-05-26 | — | — | US | disclosed |