⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydantoin SCHEMBL27705088 | 0.97 | CRBN (0.52) | — | |
| Hydantoin SCHEMBL27690 | 0.97 | — | — | |
| Hydantoin SCHEMBL7285865 | 0.97 | — | — | |
| Hydantoin SCHEMBL1786052 | 0.94 | — | — | |
| Hydantoin SCHEMBL8639680 | 0.94 | — | — | |
| Hydantoin SCHEMBL3246334 | 0.94 | — | — | |
| Hydantoin SCHEMBL2224461 | 0.94 | — | — | |
| Hydantoin SCHEMBL10578141 | 0.94 | — | — | |
| Hydantoin SCHEMBL10770473 | 0.94 | — | — | |
| Hydantoin SCHEMBL753774 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145247-A | POLYEPOXIDES | CIBA-GEIGY CORPORATION (US) | 1979-03-20 | — | — | US | claimed |
| US-20100298342-A1 | Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's Disease | MERCK & CO., INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-20090214610-A1 | BENZOIC ACID CONTAINING COMPOSITION FOR MAINTAINING HYDANTOINYLATED POLYMERS IN A BIOCIDALLY ACTIVE STATE | HALOSOURCE, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| EP-2063889-A2 | SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Merck & Co., Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008030412-A2 | SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2008-03-13 | — | — | WO | disclosed |
| EP-1863346-A1 | BENZOIC ACID CONTAINING COMPOSITION FOR MAINTAINING HYDANTOINYLATED POLYMERS IN A BIOCIDALLY ACTIVE STATE | Halosource, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006105379-A1 | BENZOIC ACID CONTAINING COMPOSITION FOR MAINTAINING HYDANTOINYLATED POLYMERS IN A BIOCIDALLY ACTIVE STATE | HALOSOURCE, INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-1678078-A1 | METHODS AND ARTICLES FOR MAINTAINING HYDANTOINYLATED POLYMERS IN A BIOCIDALLY ACTIVE STATE | Vanson Halosource, Inc. (US) | 2006-07-12 | — | — | EP | disclosed |
| US-7014781-B2 | Methods and articles for maintaining hydantoinylated polymers in a biocidally active state | VANSON HALOSOURCE, INC. (US) | 2006-03-21 | — | — | US | disclosed |
| US-20050249694-A1 | Methods and articles for maintaining hydantoinylated polymers in a biocidally active state | VANSON HALOSOURCE, INC. (US) | 2005-11-10 | — | — | US | disclosed |
| US-20050104034-A1 | Methods and articles for maintaining hydantoinylated polymers in a biocidally active state | VANSON HALOSOURCE, INC. (US) | 2005-05-19 | — | — | US | disclosed |
| WO-2005033004-A1 | METHODS AND ARTICLES FOR MAINTAINING HYDANTOINYLATED POLYMERS IN A BIOCIDALLY ACTIVE STATE | VANSON HALOSOURCE, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| EP-1064256-B1 | BICYCLO [2.2.1] HEPTANES AND RELATED COMPOUNDS | PFIZER PROD INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1396273-A1 | Bicyclo(2.2.1.)heptanes and related compounds | Pfizer Products Inc. (US) | 2004-03-10 | — | — | EP | disclosed |
| EP-1064256-A1 | BICYCLO [2.2.1] HEPTANES AND RELATED COMPOUNDS | Pfizer Products Inc. (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6136861-A | Bicyclo[2.2.1]heptanes and related compounds | PFIZER INC (US) | 2000-10-24 | — | — | US | disclosed |
| WO-1999047490-A1 | BICYCLO[2.2.1]HEPTANES AND RELATED COMPOUNDS | PFIZER PRODUCTS INC. (US) | 1999-09-23 | — | — | WO | disclosed |