Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785728 | 0.85 | QPCT (0.52) | EHMT2QPCTSLC6A2SLC6A4 | |
| SCHEMBL6160138 | 0.73 | SLC6A4 (0.54) | MEN1KMT2APKMSLC6A2SLC6A4 | |
| SCHEMBL13800328 | 0.72 | CHRM2 (0.46) | MAPK1HTTMEN1KMT2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL22797859 | 0.72 | SLC6A2 (0.53) | MEN1KMT2APKMSLC6A2SLC6A4 | |
| SCHEMBL9874311 | 0.72 | MAPK1 (0.53) | MAPK1OPRK1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4116208 | 0.72 | CHRM2 (0.45) | MAPK1HTTMEN1KMT2ASLC6A2 | |
| SCHEMBL2995935 | 0.71 | SLC6A4 (0.54) | MEN1KMT2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5181656 | 0.69 | SLC6A2 (0.42) | MAPK1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL923866 | 0.69 | TACR1 (0.55) | QPCTSLC6A2SLC6A4 | |
| SCHEMBL7259641 | 0.69 | SLC6A4 (0.38) | OPRK1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244723-A2 | Benzothiazinone derivatives, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-11 | — | — | EP | disclosed |