Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18543677 | 0.98 | SIGMAR1 (0.37) | SIGMAR1CYP1A2EPHX1ESR2UGT2B7 | |
| SCHEMBL18543685 | 0.95 | ESR2 (0.37) | SIGMAR1CYP1A2EPHX1ESR2 | |
| SCHEMBL18543671 | 0.93 | SIGMAR1 (0.34) | SIGMAR1CYP1A2EPHX1ESR2 | |
| SCHEMBL4640869 | 0.92 | CYP1A2 (0.37) | SIGMAR1CYP1A2EPHX1ESR2 | |
| SCHEMBL473472 | 0.90 | — | — | |
| SCHEMBL10775532 | 0.90 | SIGMAR1 (0.31) | SIGMAR1EPHX1 | |
| SCHEMBL18543669 | 0.88 | ESR2 (0.38) | SIGMAR1CYP1A2EPHX1ESR2 | |
| SCHEMBL23292776 | 0.87 | SIGMAR1 (0.50) | SIGMAR1CYP1A2EPHX1ESR2KDM5A | |
| SCHEMBL23292781 | 0.87 | SIGMAR1 (0.50) | SIGMAR1CYP1A2EPHX1ESR2KDM5A | |
| SCHEMBL9558015 | 0.87 | SIGMAR1 (0.50) | SIGMAR1CYP1A2EPHX1ESR2KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364348-B2 | Thermoplastic resin composition and molded article comprising the same | LOTTE ADVANCED MATERIALS CO., LTD. (KR) | 2019-07-30 | — | — | US | disclosed |
| EP-3135728-B1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME | LOTTE ADVANCED MAT CO LTD (KR) | 2018-03-07 | — | — | EP | disclosed |
| US-20170058122-A1 | Thermoplastic Resin Composition and Molded Article Comprising the Same | LOTTE ADVANCED MATERIALS CO., LTD. (KR) | 2017-03-02 | — | — | US | disclosed |
| US-20170058121-A1 | Thermoplastic Resin Composition and Molded Article Comprising the Same | LOTTE ADVANCED MATERIALS CO., LTD. (KR) | 2017-03-02 | — | — | US | disclosed |
| EP-3135728-A1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME | Lotte Advanced Materials Co., Ltd. (KR) | 2017-03-01 | — | — | EP | disclosed |
| EP-0245864-A2 | Cyclohexanedimethanol/diamine mixtures as RIM extenders | THE DOW CHEMICAL COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
| US-4659747-A | HEAT RESISTANCE | THE DOW CHEMICAL COMPANY (US) | 1987-04-21 | — | — | US | disclosed |