Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365370 | 0.73 | PPARD (0.38) | PPARDCCR8KCNH2HSD17B10KDM4E | |
| SCHEMBL8120470 | 0.69 | MAPT (0.44) | HIF1AEPAS1CCR8KCNH2HSD17B10 | |
| SCHEMBL2564022 | 0.67 | HIF1A (0.38) | HIF1AEPAS1PPARDALDH1A1NPC1 | |
| SCHEMBL13805579 | 0.67 | HTR2C (0.55) | HIF1AEPAS1PPARDCCR8KCNH2 | |
| SCHEMBL7300235 | 0.66 | CA12 (0.43) | HIF1AEPAS1CCR8KCNH2HSD17B10 | |
| SCHEMBL7300006 | 0.66 | HIF1A (0.41) | HIF1AEPAS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8722880 | 0.66 | TYR (0.41) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL9917550 | 0.63 | HSD17B10 (0.43) | HIF1AEPAS1PPARDHSD17B10KDM4E | |
| SCHEMBL2628506 | 0.63 | HIF1A (0.36) | HIF1AEPAS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL10754732 | 0.62 | TLR3 (0.36) | HIF1AEPAS1KDM4EALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1987007607-A1 | PYRANO (3,2-c) PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP P.L.C. (GB) | 1987-12-17 | — | — | WO | disclosed |