Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26121179 | 0.79 | CYP1A2 (0.45) | P2RX7CYP1A2FFAR2GOT1CTDSP1 | |
| SCHEMBL30556889 | 0.79 | CYP1A2 (0.45) | P2RX7CYP1A2FFAR2GOT1CTDSP1 | |
| SCHEMBL2436106 | 0.77 | P2RX7 (0.41) | P2RX7CYP1A2EPHX1GOT1CTDSP1 | |
| SCHEMBL626825 | 0.76 | CYP1A2 (0.60) | CYP1A2CYP3A4LMNA | |
| SCHEMBL29627913 | 0.76 | CYP1A2 (0.60) | CYP1A2CYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL29368712 | 0.74 | CYP1A2 (0.58) | CYP1A2CYP3A4LMNA | |
| SCHEMBL28748 | 0.74 | — | — | |
| SCHEMBL4417042 | 0.74 | — | — | |
| SCHEMBL6241867 | 0.74 | — | — | |
| SCHEMBL4788419 | 0.74 | HTT (0.47) | P2RX7CYP1A2EPHX1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254703-B2 | Therapeutically active steroidal derivatives | FORENDO PHARMA LTD (FI) | 2022-02-22 | — | — | US | disclosed |
| US-20180148441-A1 | Cycloalkyl-Linked Diheterocycle Derivatives | PFIZER INC. (US) | 2018-05-31 | — | — | US | disclosed |
| EP-0223974-A1 | N-Substituted-N-[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)-phenyl]alkanamides, carbamates and ureas | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148441-A1 | Cycloalkyl-Linked Diheterocycle Derivatives | CCNY, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCND2 | P2RX7 3127/4885CYP1A2 1768/4885EPHX1 1662/4885 |
| US-11254703-B2 | Therapeutically active steroidal derivatives | HSD17B11, NR5A1, CYP17A1 | P2RX7 3482/4885CYP1A2 61/4885EPHX1 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.