SCHEMBL107725

SCHEMBL107725

O=C(O)C(O)SCC(O)CO

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.40
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
PDE4A P27815 1/20 0.33
USP2 O75604 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104266 0.77 OR51E2 (0.37) OR51E2LMNAALDH1A1PDE4A
SCHEMBL1104285 0.74 HTT (0.36) OR51E2LMNAALDH1A1
SCHEMBL13446920 0.74 HTT (0.36) OR51E2LMNAALDH1A1
SCHEMBL916417 0.73 TP53 (0.41) OR51E2
SCHEMBL2136468 0.73 TP53 (0.41) ALDH1A1
SCHEMBL26444939 0.71 LMNA (0.36) OR51E2LMNAALDH1A1SLC22A6THRB
SCHEMBL10419495 0.71 TSHR (0.37) OR51E2LMNAALDH1A1SLC22A6THRB
SCHEMBL9140383 0.70 OR51E2 (0.31) OR51E2
SCHEMBL10297576 0.67
SCHEMBL3519253 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4382172-B1 COMPOSITION FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2026-03-11 EP claimed
US-12458576-B2 Method for removing color from artificially colored hair L'OREAL (FR) 2025-11-04 US claimed
EP-4577183-A1 HAIR RE-FORMING COMPOSITION COMPRISING MALIC ACID AND A BETAINE Wella Germany GmbH (DE) 2025-07-02 EP claimed
WO-2025098834-A1 HAIR RE-FORMING COMPOSITION COMPRISING MALIC ACID AND A BETAINE WELLA GERMANY GMBH (DE) 2025-05-15 WO claimed
EP-4382172-A1 COMPOSITION FOR PERMANENT SHAPING OF HUMAN HAIR Kao Germany GmbH (DE) 2024-06-12 EP claimed
US-20240173451-A1 FRAGRANCE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME Exuud, Inc. 2024-05-30 US claimed
WO-2024111582-A1 PERACETIC ACID MEASURING DEVICE CALIBRATION METHOD AND PERACETIC ACID METER CALIBRATION SYSTEM オリンパス株式会社 2024-05-30 WO claimed
US-20240122833-A1 METHOD FOR REMOVING COLOR FROM ARTIFICIALLY COLORED HAIR L'OREAL (FR) 2024-04-18 US claimed
CN-117729945-A Fragrance composition, method of making and articles comprising the same 埃克苏德公司 2024-03-19 CN claimed
EP-4294465-A1 FRAGRANCE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME Neerja Ventures, LLC (US) 2023-12-27 EP claimed
CN-1286976-A Long-acting hair-waving method for preapplying polymer composition containing at least one kind of anion OREAL (FR) 2001-03-14 CN claimed
US-6187302-B1 THIOL-BEARING REDUCING AGENT IN AQUEOUS MEDIUM, AND AT LEAST ONE THICKENING POLYMER IN AQUEOUS MEDIUM, SAID THICKENING POLYMER BEING IN THE FORM OF AN AQUEOUS DISPERSION, AN OILY DISPERSION, OR A REVERSE EMULSION L'OREAL S.A. (FR) 2001-02-13 US claimed
US-5925366-A PERMEATION/BINDING AGENT, THIO CROSSLINKING AGENT, AND CHELATE COMPOUND REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-07-20 US claimed
US-5785959-A MIXTURE CONTAINING A PERMEATION/BINDING AGENT, A THIO CROSSLINKING AGENT, A CHELATING AGENT, WATER AND AN OIL REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-07-28 US claimed
WO-1998006376-A1 NAIL STRENGTHENING COMPOSITIONS AND A METHOD FOR STRENGTHENING NAILS REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-02-19 WO claimed
US-5609860-A Curly hair-straightening composition KAO CORPORATION (JP) 1997-03-11 US claimed
US-5378454-A Hydrogen peroxide activator, ammonium thioglycolate reducing agent and less active glyceryl thioglycolate JOHN PAUL MITCHELL SYSTEMS (US) 1995-01-03 US claimed
US-4273143-A Permanent wave composition ZOTOS INTERNATIONAL, INC. (US) 1981-06-16 US claimed
US-4214596-A APPLYING MERCAPTAN-CONTAINING SOLUTION, NEUTRALIZATION WITH OXIDIZING AGENT HELENE CURTIS INDUSTRIES, INC. (US) 1980-07-29 US claimed
US-4158704-A ESTER OF THIOGLYCOLIC ACID AS REDUCING AGENT REVLON INC. (US) 1979-06-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458576-B2 Method for removing color from artificially colored hair TYR, COXFA4L2, CAT OR51E2 3240/4885LMNA 2349/4885ALDH1A1 434/4885
US-20240122833-A1 METHOD FOR REMOVING COLOR FROM ARTIFICIALLY COLORED HAIR TYR, COXFA4L2, CAT OR51E2 3240/4885LMNA 2349/4885ALDH1A1 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.