Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 13/20 | 0.67 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936634 | 0.90 | PRKD1 (0.69) | PRKD1 | |
| SCHEMBL6924458 | 0.90 | PRKD1 (0.62) | PRKD1DRD2DRD4 | |
| SCHEMBL1056077 | 0.87 | PRKD1 (0.76) | PRKD1 | |
| SCHEMBL959852 | 0.86 | PRKD1 (0.68) | PRKD1 | |
| SCHEMBL6923808 | 0.82 | PRKD1 (0.62) | PRKD1 | |
| SCHEMBL1057491 | 0.81 | PRKD1 (0.63) | PRKD1 | |
| SCHEMBL967019 | 0.81 | PRKD1 (1.00) | PRKD1 | |
| SCHEMBL935732 | 0.79 | PRKD1 (0.93) | PRKD1 | |
| SCHEMBL6922501 | 0.79 | PRKD1 (0.80) | PRKD1 | |
| SCHEMBL936452 | 0.76 | PRKD1 (0.74) | PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |