⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1204186 | 1.00 | — | — | |
| SCHEMBL150257 | 1.00 | — | — | |
| SCHEMBL13875821 | 0.82 | — | — | |
| SCHEMBL7154999 | 0.80 | CA2 (0.50) | — | |
| SCHEMBL14501495 | 0.80 | CA2 (0.55) | — | |
| SCHEMBL740693 | 0.80 | — | — | |
| SCHEMBL18817541 | 0.80 | CA2 (0.50) | — | |
| SCHEMBL4135508 | 0.80 | — | — | |
| SCHEMBL6125258 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL27847677 | 0.78 | CA2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062754-B | Preparation method of intermediate for synthesizing Dorzagliatin | 深圳市华先医药科技有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-112062754-A | Preparation method of intermediate for synthesizing Dorzagliatin | 深圳市华先医药科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-105315255-B | A kind of synthetic method of resolving agent hydrogen phthalic acid isopropylidene glyceride | 上海予利生物科技股份有限公司 | 2017-12-26 | — | — | CN | claimed |
| CN-105315255-A | Synthetic method of resolving agent hydrogen isopropylidene glycerol phthalate | SHANGHAI YURLIC CHEMICAL S&T CO LTD | 2016-02-10 | — | — | CN | claimed |
| WO-1996029325-A1 | HOMOCHIRAL COMPOUNDS FOR THE PREPARATION OF KETOCONAZOLE, TERCONAZOLE AND RELATED ANTIFUNGAL DRUGS | LABORATORIOS MENARINI S.A. (ES) | 1996-09-26 | — | — | WO | claimed |
| US-20250263399-A1 | CBL-B MODULATORS AND USES THEREOF | SCHRÖDINGER, INC. | 2025-08-21 | — | — | US | disclosed |
| US-12325697-B2 | CBL-B modulators and uses thereof | NIMBUS CLIO, INC. (US) | 2025-06-10 | — | — | US | disclosed |
| US-12275727-B2 | Compound containing structure of a five-membered heteroaromatic ring, pharmaceutical compositions thereof and applications thereof | 280 BIO, INC. (US) | 2025-04-15 | — | — | US | disclosed |
| CN-114163437-B | Substituted pyrazolo [1,5-a ] pyridine compounds as RET kinase inhibitors | 阿雷生物药品公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4488275-A1 | COMPOUND CONTAINING FIVE-MEMBERED HETEROAROMATIC RING STRUCTURE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Yingli Pharmaceutical Co., Ltd (CN) | 2025-01-08 | — | — | EP | disclosed |
| US-11998545-B2 | Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2024-06-04 | — | — | US | disclosed |
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2008079814-A2 | MAPK/ERK KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-03 | — | — | WO | disclosed |
| WO-2007085540-A1 | 1H-INDAZ0L-4-YL-2 , 4-PYRIMIDINEDIAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-08-02 | — | — | WO | disclosed |
| US-20070161787-A1 | C-glycoside derivatives and salts thereof | ASTELLAS PHARMA INC. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-7202350-B2 | C-glycoside derivatives and salts thereof | ASTELLAS PHARMA INC. (JP) | 2007-04-10 | — | — | US | disclosed |
| US-20060122126-A1 | C-glycoside derivatives and salts thereof | ASTELLAS PHARMA INC. (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1609785-A1 | C-GLYCOSIDE DERIVATIVES AND SALTS THEREOF | Astellas Pharma Inc. (JP) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004046118-A2 | 2-4-(DI-PHENYL-AMINO)-PYRIMIDINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |
| WO-1996029325-A1 | HOMOCHIRAL COMPOUNDS FOR THE PREPARATION OF KETOCONAZOLE, TERCONAZOLE AND RELATED ANTIFUNGAL DRUGS | LABORATORIOS MENARINI S.A. (ES) | 1996-09-26 | — | — | WO | disclosed |