Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.65 |
| ▸ | GLB1 | P16278 | 4/20 | 0.65 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034127 | 0.93 | B4GALT1 (0.62) | GBA1GLB1B4GALT1HDAC4HDAC10 | |
| SCHEMBL1034680 | 0.93 | B4GALT1 (0.62) | GBA1GLB1B4GALT1HDAC4HDAC10 | |
| SCHEMBL1034677 | 0.93 | B4GALT1 (0.62) | GBA1GLB1B4GALT1HDAC4HDAC10 | |
| SCHEMBL1034124 | 0.93 | B4GALT1 (0.62) | GBA1GLB1B4GALT1HDAC4HDAC10 | |
| SCHEMBL1035610 | 0.82 | B4GALT1 (0.53) | GBA1GLB1B4GALT1HDAC4HDAC10 | |
| SCHEMBL1035609 | 0.82 | B4GALT1 (0.53) | GBA1GLB1B4GALT1HDAC4HDAC10 | |
| SCHEMBL4139459 | 0.80 | HDAC4 (0.75) | GBA1GLB1HDAC4HDAC10HDAC6 | |
| SCHEMBL4142506 | 0.79 | HDAC4 (0.77) | GBA1GLB1HDAC4HDAC10HDAC6 | |
| SCHEMBL4782146 | 0.78 | HDAC4 (0.69) | GBA1GLB1HDAC4HDAC10HDAC6 | |
| SCHEMBL4126957 | 0.78 | HDAC4 (0.71) | GBA1GLB1HDAC4HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112184-A1 | COMPOUNDS WITH GLYCIDIC STRUCTURE ACTIVE IN THE THERAPY OF SYSTEMIC AND LOCAL INFLAMMATION | NICOTRA, FRANCESCO (IT) | 2011-05-12 | — | — | US | claimed |
| EP-2276773-A2 | COMPOUNDS WITH GLYCIDIC STRUCTURE ACTIVE IN THE THERAPY OF SYSTEMIC AND LOCAL INFLAMMATION | La Ferla, Barbara (IT) | 2011-01-26 | — | — | EP | claimed |
| WO-2009135673-A2 | COMPOUNDS WITH GLYCIDIC STRUCTURE ACTIVE IN THE THERAPY OF SYSTEMIC | LA FERLA BARBARA (IT) | 2009-11-12 | — | — | WO | claimed |
| US-20110112184-A1 | COMPOUNDS WITH GLYCIDIC STRUCTURE ACTIVE IN THE THERAPY OF SYSTEMIC AND LOCAL INFLAMMATION | NICOTRA, FRANCESCO (IT) | 2011-05-12 | — | — | US | disclosed |
| US-20110112184-A1 | COMPOUNDS WITH GLYCIDIC STRUCTURE ACTIVE IN THE THERAPY OF SYSTEMIC AND LOCAL INFLAMMATION | NICOTRA, FRANCESCO (IT) | 2011-05-12 | — | — | US | disclosed |
| WO-2009135673-A2 | COMPOUNDS WITH GLYCIDIC STRUCTURE ACTIVE IN THE THERAPY OF SYSTEMIC | LA FERLA BARBARA (IT) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112184-A1 | COMPOUNDS WITH GLYCIDIC STRUCTURE ACTIVE IN THE THERAPY OF SYSTEMIC AND LOCAL INFLAMMATION | C9, CCR10, CA9 | GBA1 272/4885GLB1 857/4885B4GALT1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.