B4GALT1

Beta-1,4-galactosyltransferase 1 · P15291 · B4GALT1 on Sugi Atlas →

1,525 patent compounds predicted against B4GALT1, 1,243 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL12015070 SCHEMBL12015070 0.66 4/20
SCHEMBL12361503 SCHEMBL12361503 0.66 4/20
SCHEMBL14088636 SCHEMBL14088636 0.66 4/20
SCHEMBL14414538 SCHEMBL14414538 0.66 4/20
SCHEMBL14583153 SCHEMBL14583153 0.66 4/20
SCHEMBL12108959 SCHEMBL12108959 0.61 4/20
SCHEMBL13614408 SCHEMBL13614408 0.61 4/20
SCHEMBL14017122 SCHEMBL14017122 0.61 4/20
SCHEMBL14027760 SCHEMBL14027760 0.55 4/20
SCHEMBL14654380 SCHEMBL14654380 0.49 4/20
SCHEMBL15935830 SCHEMBL15935830 0.49 4/20
SCHEMBL13614520 SCHEMBL13614520 0.48 4/20
SCHEMBL14017350 SCHEMBL14017350 0.48 4/20
SCHEMBL13614496 SCHEMBL13614496 0.48 4/20
SCHEMBL14017312 SCHEMBL14017312 0.48 4/20
SCHEMBL14628959 SCHEMBL14628959 0.39 4/20
SCHEMBL14598992 SCHEMBL14598992 0.38 4/20
SCHEMBL13614486 SCHEMBL13614486 0.75 3/20
SCHEMBL13614499 SCHEMBL13614499 0.75 3/20
SCHEMBL14017280 SCHEMBL14017280 0.75 3/20

Clinical trials — most relevant to B4GALT1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Role of SGLT2i in Management of Moderate AS PHASE2/PHASE3UNKNOWN
Сlinical Trial of Efficacy and Safety of Prospekta in the Treatment of Post-COVID-19 Asthenia. PHASE3COMPLETED
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer PHASE1/PHASE2COMPLETED
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1/PHASE2RECRUITING
OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients With Neuronopathic Gaucher Disease PHASE2COMPLETED
Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis PHASE1/PHASE2ACTIVE_NOT_RECRUITING
N-Acetyl-L-Leucine for GM2 Gangliosidosis (Tay-Sachs and Sandhoff Disease) PHASE2COMPLETED
Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy PHASE1NOT_YET_RECRUITING
Autologous Stem Cell Transplantation of Cells Engineered to Express Alpha-Galactosidase A in Patients With Fabry Disease PHASE1COMPLETED
Study to Compare a Dose of Telotristat Etiprate in Subjects With Renal Impairment With Matched Subjects With Normal Renal Function PHASE1COMPLETED
Investigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females PHASE1COMPLETED
Glycosylation in Patients With Galactosaemia nanCOMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
Fibrosis, Inflammation, Oxygenation of Renal Tissue In FabrY Disease nanRECRUITING
Biomarker for Gangliosidosis: BioGM1/BioGM2 (BioGM1/GM2) nanWITHDRAWN
Beraprost Sodium and Arterial Stiffness in Patients With Type 2 Diabetic Nephropathy nanUNKNOWN
the Role of cArdiac Inflammation, endoThelial Dysfunction, and FIbrosis in fabrY Disease nanRECRUITING
Secondary Lactose Intolerance Due to Chronic Norovirus Infection nanCOMPLETED
Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation nanCOMPLETED
BMN 110 US Expanded Access Program nanAPPROVED_FOR_MARKETING
Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption nanUNKNOWN
Inflammatory Pathways and Cardiac Growth Factors Associated With Fabry Disease Cardiomyopathy nanUNKNOWN
The Natural History of Alpha-Mannosidosis nanCOMPLETED
Inactive FSH in Galactosemia nanUNKNOWN
Fabry Disease in High-risk Patients With Left Ventricular Hypertrophy: Prevalence and Implementation of a Clinical Score nanACTIVE_NOT_RECRUITING
Lyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher Disease nanCOMPLETED
A Retrospective Study to Identify New Omics Biomarkers of Chronic/Persistent Low Back Pain nanCOMPLETED
Intervention and Outcomes in Duarte Galactosemia nanCOMPLETED
Biomarker for Mannosidosis Disease (BioMannosidosis) nanWITHDRAWN
Pregnancy Chances in Classic Galactosemia nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a B4GALT1 binder may also engage these)

ProteinNameSimilarity
P15535 1.000 P15535 →
Q80WN9 1.000 Q80WN9 →
Q9Z2Y2 1.000 Q9Z2Y2 →
P08037 1.000 P08037 →
A8Y1P7 0.999 A8Y1P7 →
Q9JMK0 0.998 Q9JMK0 →
O60909 0.997 O60909 →
Q80WN8 0.997 Q80WN8 →
A0A1S6M251 0.997 A0A1S6M251 →
Q5EA87 0.997 Q5EA87 →
O43286 0.997 O43286 →
Q91YY2 0.997 Q91YY2 →
Q6P768 0.996 Q6P768 →
O60512 0.996 O60512 →
Q66HH1 0.996 Q66HH1 →
Q9GUM2 0.995 Q9GUM2 →
Q80WN7 0.994 Q80WN7 →
Q5NVN3 0.993 Q5NVN3 →
Q9WVK5 0.992 Q9WVK5 →
Q3YL68 0.992 Q3YL68 →
Q9JJ04 0.991 Q9JJ04 →
Q9P2W7 0.991 Q9P2W7 →
Q7KN92 0.991 Q7KN92 →
Q9VAQ8 0.991 Q9VAQ8 →
Q8IXK2 0.991 Q8IXK2 →
O60513 0.990 O60513 →
Q9UBX8 0.990 Q9UBX8 →
Q5EA41 0.990 Q5EA41 →
O88419 0.989 O88419 →
Q6P6V1 0.989 Q6P6V1 →