Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TGM1 | P22735 | 1/20 | 0.31 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23092171 | 0.87 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1CYP2C19 | |
| SCHEMBL11461905 | 0.80 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1CYP2C19 | |
| SCHEMBL27992132 | 0.80 | TSHR (0.35) | TSHRCYP2C19SMN1; SMN2GRIK1GRIK2 | |
| SCHEMBL6906222 | 0.78 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2GRIK1GRIK2 | |
| SCHEMBL28679718 | 0.77 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1CYP2C19 | |
| SCHEMBL7114237 | 0.76 | TSHR (0.37) | TSHRALDH1A1MAPK1TDP1CYP2C19 | |
| SCHEMBL15444305 | 0.74 | TSHR (0.58) | TSHRALDH1A1MAPK1TDP1CYP2C19 | |
| SCHEMBL19315489 | 0.74 | TSHR (0.47) | TSHRALDH1A1MAPK1TDP1CYP2C19 | |
| SCHEMBL22750295 | 0.74 | TGFBR1 (0.43) | TSHRSMN1; SMN2 | |
| SCHEMBL5823623 | 0.72 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005770-A1 | CERIA FOR USE AS AN ANTIMICROBIAL BARRIER AND DISINFECTANT IN A WOUND DRESSING | MOLYCORP MINERALS LLC (US) | 2011-01-13 | — | — | WO | disclosed |
| US-5633049-A | POLYCARBONATE AND POLYMETHYL METHACRYLATE WINDOWS, REACTION PRODUCT OF AN ACRYLIC AMIDE AND A TRIACRYLATE OR TETRAACRYLATE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-27 | — | — | US | disclosed |