Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322230 | 1.00 | HRH3 (0.48) | HRH3MAPTLSSSIGMAR1HRH1 | |
| SCHEMBL9322156 | 0.97 | HRH3 (0.52) | HRH3MAPTSIGMAR1HRH1SLC6A4 | |
| SCHEMBL9322439 | 0.97 | HRH3 (0.52) | HRH3MAPTSIGMAR1HRH1SLC6A4 | |
| SCHEMBL9322488 | 0.97 | HRH3 (0.52) | HRH3MAPTSIGMAR1HRH1SLC6A4 | |
| SCHEMBL9323566 | 0.97 | HRH3 (0.52) | HRH3MAPTSIGMAR1HRH1SLC6A4 | |
| SCHEMBL9324566 | 0.97 | HRH3 (0.52) | HRH3MAPTSIGMAR1HRH1SLC6A4 | |
| SCHEMBL9322241 | 0.95 | HRH3 (0.45) | HRH3MAPTLSSSIGMAR1HRH1 | |
| SCHEMBL9324742 | 0.95 | HRH3 (0.48) | HRH3MAPTSIGMAR1 | |
| SCHEMBL9321363 | 0.93 | HRH3 (0.42) | HRH3MAPTLSSSLC6A4 | |
| SCHEMBL10774584 | 0.93 | HRH3 (0.42) | HRH3MAPTLSSSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235942-A1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |