Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322161 | 0.97 | HRH3 (0.41) | HRH3MAPTLSSSLC6A4CYP1A2 | |
| SCHEMBL9322145 | 0.97 | HRH3 (0.41) | HRH3MAPTLSSSLC6A4CYP1A2 | |
| SCHEMBL9322230 | 0.95 | HRH3 (0.48) | HRH3MAPTLSSHRH1SLC6A4 | |
| SCHEMBL10774443 | 0.95 | HRH3 (0.48) | HRH3MAPTLSSHRH1SLC6A4 | |
| SCHEMBL9324566 | 0.95 | HRH3 (0.52) | HRH3MAPTHRH1SLC6A4SIGMAR1 | |
| SCHEMBL9322488 | 0.95 | HRH3 (0.52) | HRH3MAPTHRH1SLC6A4SIGMAR1 | |
| SCHEMBL9322439 | 0.95 | HRH3 (0.52) | HRH3MAPTHRH1SLC6A4SIGMAR1 | |
| SCHEMBL9324674 | 0.95 | HRH3 (0.38) | HRH3MAPTLSSSLC6A4FPR3 | |
| SCHEMBL9323566 | 0.95 | HRH3 (0.52) | HRH3MAPTHRH1SLC6A4SIGMAR1 | |
| SCHEMBL9322156 | 0.95 | HRH3 (0.52) | HRH3MAPTHRH1SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0235942-A1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |