Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11674990 | 0.88 | CA4 (0.54) | CA4FAHD1MEN1LDHABLM | |
| Sulfurous Acid SCHEMBL9489555 | 0.88 | CA1 (0.46) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL226679 | 0.85 | CA4 (0.40) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL3326642 | 0.84 | CA4 (0.46) | CA4FAHD1MEN1LDHABLM | |
| Sulfurous Acid SCHEMBL28286497 | 0.84 | — | — | |
| Sulfurous Acid SCHEMBL28442692 | 0.84 | — | — | |
| Bicarbonate SCHEMBL8356204 | 0.84 | CA1 (0.55) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL11794385 | 0.84 | CA1 (0.55) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL8594161 | 0.84 | CA1 (0.55) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL11203856 | 0.84 | CA1 (0.55) | CA4FAHD1MEN1LDHABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659651-A | STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| US-4343873-A | SILVER HALIDE EMULSION EXPOSED TO LASER THROUGH LIGHT-SCATTERING LAYER | FUJI PHOTO FILM COMPANY, LTD. (JP) | 1982-08-10 | — | — | US | disclosed |
| US-4322494-A | SENSITIZERS FOR SILVER HALIDE EMULSIONS; ZWITTERIONS | FUJI PHOTO FILM CO., LTD. (JP) | 1982-03-30 | — | — | US | disclosed |
| US-4286044-A | HIGH QUALITY DOT IMAGES USING MEROCYANINE DYES; PHOTOLITHOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |