SCHEMBL1077565

SCHEMBL1077565

OC[C@@H]1COC[C@@H](CO)O1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 8/20 0.38
CHRM3 P20309 8/20 0.38
CHRM4 P08173 7/20 0.38
CHRM5 P08912 7/20 0.38
CHRM1 P11229 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1077566 1.00 CHRM2 (0.38) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL1077568 1.00 CHRM2 (0.38) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL15578861 1.00 CHRM2 (0.38) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL15520444 0.87 ALDH1A1 (0.42) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL15520445 0.87 ALDH1A1 (0.42) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL15520446 0.87 ALDH1A1 (0.42) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL343634 0.82
SCHEMBL16037715 0.82
SCHEMBL21350447 0.82
SCHEMBL24933685 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268596-B1 COMPOSITION COMPRISING GLYCEROL, PROCESS FOR OBTAINING SAME AND USE THEREOF IN THE MANUFACTURE OF DICHLOROPROPANOL SOLVAY (BE) 2017-05-31 EP claimed
EP-2895449-A1 PROCESS OF STRIPPING A LIQUID MEDIUM Solvay SA (BE) 2015-07-22 EP claimed
WO-2014040883-A1 PROCESS OF STRIPPING A LIQUID MEDIUM SOLVAY SA (BE) 2014-03-20 WO claimed
US-8507643-B2 Composition comprising glycerol, process for obtaining same and use thereof in the manufacture of dichloropropanol SOLVAY S.A. (BE) 2013-08-13 US claimed
EP-2268596-B1 COMPOSITION COMPRISING GLYCEROL, PROCESS FOR OBTAINING SAME AND USE THEREOF IN THE MANUFACTURE OF DICHLOROPROPANOL SOLVAY (BE) 2017-05-31 EP disclosed
EP-2170793-B1 MANUFACTURE OF EPICHLOROHYDRIN SOLVAY (BE) 2016-08-10 EP disclosed
EP-2895449-A1 PROCESS OF STRIPPING A LIQUID MEDIUM Solvay SA (BE) 2015-07-22 EP disclosed
WO-2014040883-A1 PROCESS OF STRIPPING A LIQUID MEDIUM SOLVAY SA (BE) 2014-03-20 WO disclosed
EP-2708525-A1 Process of stripping a liquid medium Solvay SA (BE) 2014-03-19 EP disclosed
EP-2669308-A1 Process for manufacturing an epoxy resin SOLVAY SA (BE) 2013-12-04 EP disclosed
US-8536381-B2 Process for purifying hydrogen chloride SOLVAY SA (BE) 2013-09-17 US disclosed
US-8507643-B2 Composition comprising glycerol, process for obtaining same and use thereof in the manufacture of dichloropropanol SOLVAY S.A. (BE) 2013-08-13 US disclosed
US-5338870-A Thermal condensation of polyhydric alcohols to form polyethercyclicpolyols SHELL OIL COMPANY (US) 1994-08-16 US disclosed
US-5302695-A Polycondensation of epoxy alcohols with polyhydric alcohols and thermal condensation to form polyethercyclicpolyols SHELL OIL COMPANY (US) 1994-04-12 US disclosed
US-5302728-A Polycondensation of phenolic hydroxyl-containing compounds and polyhydric alcohols and thermal condensation to form polyethercyclipolyols SHELL OIL COMPANY (US) 1994-04-12 US disclosed
US-5233055-A Heating to condense a reaction mixture of polyols, polyol precurgors and/or cyclic derivatives water, continousing condensation and mixing in a epoxide before completion of condensation SHELL OIL COMPANY (US) 1993-08-03 US disclosed
US-5204444-A Polycondensation of epoxy alcohols with polyhdric alcohols and thermal condensation to form polyethercyclicpolyols SHELL OIL COMPANY (US) 1993-04-20 US disclosed
US-5198532-A Polycondensation of epihalohydrin and polyhydric alcohols and thermal condensation to form polyethercyclicpolyols SHELL OIL COMPANY (US) 1993-03-30 US disclosed
EP-0505002-A2 Method of preparing polyethercyclicpolyols SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-09-23 EP disclosed
EP-0505000-A2 Method of preparing polyethercyclicpolyols SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-09-23 EP disclosed