Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 6/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640080 | 0.92 | IDH1 (0.35) | MAPTHTTL3MBTL1HSD17B1HSD17B2 | |
| SCHEMBL1031656 | 0.90 | MAPT (0.36) | MAPTHTTL3MBTL1PPARAPPARD | |
| SCHEMBL1035702 | 0.82 | IDH1 (0.36) | MAPTHTTL3MBTL1HSD17B1HSD17B2 | |
| SCHEMBL1035148 | 0.79 | PPARD (0.41) | PPARAPPARDPTGDR2LTB4RPPARG | |
| SCHEMBL1036145 | 0.78 | PPARA (0.38) | PPARAPPARDPTGDR2PPARG | |
| SCHEMBL1081800 | 0.76 | ESR1 (0.40) | PPARAPPARDHSD17B1HSD17B2PPARG | |
| SCHEMBL1034628 | 0.72 | ALDH1A1 (0.37) | MAPTHTTL3MBTL1PPARAHSD17B1 | |
| SCHEMBL1032853 | 0.71 | PPARA (0.40) | PPARAPPARDPTGDR2PPARG | |
| SCHEMBL1031655 | 0.70 | PPARD (0.43) | PPARAPPARDPTGDR2LTB4RPPARG | |
| SCHEMBL1035701 | 0.67 | ESR1 (0.42) | MAPTPPARAPPARDPPARGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424917-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2019-01-09 | — | — | EP | disclosed |
| EP-2277874-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2018-06-27 | — | — | EP | disclosed |
| US-8648208-B2 | Activating agent for peroxisome proliferator activated receptor | NIPPON CHEMIPHAR CO. LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20110098480-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO. LTD. (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-2277874-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2011-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098480-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | PPARA, PPARG, PPARD | MAPT 4843/4885HTT 4503/4885L3MBTL1 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.