Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540188 | 0.98 | CYP2C19 (0.47) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| Bromide SCHEMBL11307528 | 0.96 | CYP2C19 (0.46) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11078901 | 0.85 | CYP2C19 (0.47) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4269743 | 0.85 | CYP2C19 (0.43) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL251653 | 0.84 | CYP2C19 (0.42) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL859875 | 0.84 | CYP2C19 (0.42) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL246821 | 0.84 | CYP2C19 (0.42) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL27316642 | 0.83 | CYP2C19 (0.44) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL15957004 | 0.82 | CYP2C19 (0.50) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL250446 | 0.81 | CYP2C19 (0.43) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112515996-B | Antibacterial hand sanitizer and preparation method thereof | 明尼苏达矿业制造医用器材（上海）有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-111172807-A | Method for constructing cationic supramolecular colloid by using native starch granules | 东北林业大学 | 2020-05-19 | — | — | CN | claimed |
| CN-105191934-B | Thimerosal, non-woven fabrics containing thimerosal and its preparation method and application | 明尼苏达矿业制造医用器材（上海）有限公司 | 2018-02-02 | — | — | CN | claimed |
| CN-105191934-A | Disinfectant, nonwoven fabric containing disinfectant, preparation method and application | 3M MEDICAL DEVICES AND MATERIAL MFG SHANGHAI CO LTD | 2015-12-30 | — | — | CN | claimed |
| EP-4294903-A1 | EFFERVESCENT GERMICIDAL COMPOSITIONS | Reckitt & Colman (Overseas) Hygiene Home Limited (GB) | 2023-12-27 | — | — | EP | disclosed |
| CN-112515996-B | Antibacterial hand sanitizer and preparation method thereof | 明尼苏达矿业制造医用器材（上海）有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-111172807-A | Method for constructing cationic supramolecular colloid by using native starch granules | 东北林业大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-109898215-A | Composite wool fabric and its manufacture craft with cold-resistant heat-preserving function | 上海恋轩实业有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-105191934-B | Thimerosal, non-woven fabrics containing thimerosal and its preparation method and application | 明尼苏达矿业制造医用器材（上海）有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-107586554-A | It is a kind of to be used to remove the refining agent of organic nitrogen compound and thiophene-type sulfide in fuel oil | 中国石油大学(华东) | 2018-01-16 | — | — | CN | disclosed |
| CN-105191934-A | Disinfectant, nonwoven fabric containing disinfectant, preparation method and application | 3M MEDICAL DEVICES AND MATERIAL MFG SHANGHAI CO LTD | 2015-12-30 | — | — | CN | disclosed |
| WO-1987006177-A1 | AQUEOUS SOLUTIONS OF ROSIN AND USE OF THE SOLUTIONS | KEMIRA KEMWOOD AB (SE) | 1987-10-22 | — | — | WO | disclosed |
| US-4333862-A | Detergent compositions comprising mixture of cationic, anionic and nonionic surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| EP-0051986-A2 | Detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1982-05-19 | — | — | EP | disclosed |
| US-4321165-A | Detergent compositions comprising cationic, anionic and nonionic surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| US-4298397-A | LIQUID PETROLEUM HYDROCARBON AND WATER; IMPROVED PAVING PENETRATION | BURRIS MICHAEL V | 1981-11-03 | — | — | US | disclosed |
| US-4289649-A | LIPID-SOLUBILIZING AMOUNT OF BOTH A NONIONIC DETERGENT AND AN IONIC DETERGENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-15 | — | — | US | disclosed |
| EP-0000224-A1 | Liquid detergent composition for improved greasy soil removal | THE PROCTER & GAMBLE COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |
| EP-0000225-A1 | Solid detergent composition for improved greasy soil removal | THE PROCTER & GAMBLE COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |
| US-4104368-A | STEARYLDIMETHYLBENZYLAMMONIUM P-AMINOBENZOATE | MILLMASTER ONYX CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |