Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955030 | 0.76 | GPR84 (0.44) | GPR84HRH3 | |
| SCHEMBL7100687 | 0.74 | DAO (0.43) | DAOIDO1TLR8TLR7KCNA3 | |
| SCHEMBL7003873 | 0.74 | GPR84 (0.41) | DAOGPR84HRH3 | |
| SCHEMBL23496251 | 0.72 | USP2 (0.44) | DAOIDO1TLR8TLR7KDM4E | |
| SCHEMBL9154367 | 0.71 | GPR84 (0.59) | GPR84 | |
| SCHEMBL2111421 | 0.71 | GPR84 (0.59) | GPR84 | |
| SCHEMBL16135390 | 0.71 | GPR84 (0.59) | GPR84 | |
| SCHEMBL2889726 | 0.71 | GPR84 (0.59) | GPR84 | |
| SCHEMBL2402381 | 0.71 | GPR84 (0.59) | GPR84 | |
| SCHEMBL8646071 | 0.71 | GPR84 (0.59) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233341-A1 | 5-Heterocyclyl-1-aryl-pyrazole | BAYER AG (DE) | 1987-08-26 | — | — | EP | disclosed |