Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722383 | 0.90 | HPGD (0.40) | BRD4MAOBCDK4CCND1PRKDC | |
| SCHEMBL10621402 | 0.86 | ATM (0.38) | MAPTBRD4MAOBAURKAPARP1 | |
| SCHEMBL10776657 | 0.79 | BRD4 (0.43) | MAPTBRD4MAOBAURKAPARP1 | |
| SCHEMBL9180131 | 0.79 | NPC1 (0.35) | MAPTBRD4KDM4ENPC1ALDH1A1 | |
| SCHEMBL5667449 | 0.73 | CDC25B (0.41) | MAPTBRD4KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL25199891 | 0.71 | KDR (0.46) | MAPTBRD4AURKAPARP1PIK3CB | |
| SCHEMBL10337010 | 0.71 | KDM4E (0.36) | MAPTKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL8438285 | 0.69 | PARP1 (0.38) | BRD4PARP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL8776952 | 0.66 | BRD4 (0.40) | MAPTBRD4PARP1PRKDCKDM4E | |
| SCHEMBL6360162 | 0.65 | MAOA (0.54) | MAPTBRD4AURKACDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705776-A | Recording material containing chromogenic 3,3-bisindolyl-4-azaphthalides | CIBA-GEIGY CORPORATION (US) | 1987-11-10 | — | — | US | disclosed |
| US-4668966-A | PRESSURE- OR HEAT-SENSITIVE RECORDING | CIBA-GEIGY CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
| US-4587343-A | COLOR FORMERS IN PRESSURE-SENSITIVE OR HEAT SENSITIVE RECORDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |
| US-4555569-A | PRESSURE AND HEAT SENSITIVE ELEMENTS | CIBA-GEIGY CORPORATION (US) | 1985-11-26 | — | — | US | disclosed |