Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 11/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679488 | 1.00 | BMP1 (0.43) | BMP1KMT2AMEN1MMP2MMP13 | |
| SCHEMBL1078022 | 0.94 | BMP1 (0.46) | BMP1KMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL6685014 | 0.94 | BMP1 (0.46) | BMP1KMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL1039183 | 0.93 | BMP1 (0.43) | BMP1KMT2AMEN1MMP2MMP13 | |
| SCHEMBL1039459 | 0.93 | BMP1 (0.45) | BMP1KMT2AMEN1MMP2MMP13 | |
| SCHEMBL6622848 | 0.93 | BMP1 (0.45) | BMP1KMT2AMEN1MMP2MMP13 | |
| SCHEMBL6624074 | 0.93 | BMP1 (0.42) | BMP1KMT2AMEN1MMP2MMP13 | |
| SCHEMBL1077208 | 0.93 | BMP1 (0.42) | BMP1KMT2AMEN1MMP2MMP13 | |
| SCHEMBL1076810 | 0.92 | BMP1 (0.53) | BMP1 | |
| SCHEMBL1077694 | 0.91 | BMP1 (0.47) | BMP1KMT2AMEN1MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480941-B1 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | AMBRILIA BIOPHARMA INC (CA) | 2011-01-26 | — | — | EP | disclosed |
| US-6528532-B1 | Benzenesulfonamide group | PHARMACOR INC. (CA) | 2003-03-04 | — | — | US | disclosed |