Sugi Predict

Sugi Predict / Targets / BMP1

BMP1

Bone morphogenetic protein 1 · P13497 · BMP1 on Sugi Atlas →

17,179 patent compounds predicted against BMP1, 8,793 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL966010 SCHEMBL966010 1.00 20/20
SCHEMBL966229 SCHEMBL966229 1.00 20/20
SCHEMBL1115835 SCHEMBL1115835 0.77 20/20
SCHEMBL1076035 SCHEMBL1076035 0.51 20/20
SCHEMBL1077866 SCHEMBL1077866 0.50 20/20
SCHEMBL1076810 SCHEMBL1076810 0.53 19/20
SCHEMBL1566106 SCHEMBL1566106 0.65 15/20
SCHEMBL609030 SCHEMBL609030 0.50 14/20
SCHEMBL1799177 SCHEMBL1799177 0.58 12/20
SCHEMBL1799131 SCHEMBL1799131 0.54 12/20
SCHEMBL1800828 SCHEMBL1800828 0.51 12/20
SCHEMBL1801225 SCHEMBL1801225 0.51 12/20
SCHEMBL1800831 SCHEMBL1800831 0.44 12/20
SCHEMBL1596230 SCHEMBL1596230 0.65 11/20
SCHEMBL1596233 SCHEMBL1596233 0.65 11/20
SCHEMBL1800811 SCHEMBL1800811 0.51 11/20
SCHEMBL1798842 SCHEMBL1798842 0.49 11/20
SCHEMBL2783856 SCHEMBL2783856 0.60 10/20
SCHEMBL2783859 SCHEMBL2783859 0.60 10/20
SCHEMBL2851917 SCHEMBL2851917 0.55 10/20

Clinical trials — most relevant to BMP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Vitamin D and Carboxy PTH Fragments in Coronary Calcification PHASE4WITHDRAWN
Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study) PHASE4COMPLETED
A Multi-center, Comparative Clinical Trial to Evaluate the Efficacy and Safety of Inject BMP in Patients Undergoing Transforaminal Lumbar Interbody Fusion PHASE3UNKNOWN
A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor PHASE1/PHASE2COMPLETED
The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect PHASE1/PHASE2COMPLETED
Parallel Study Between BMP-2 and Autologous Bone Graft After Ilizarow Treatment PHASE1COMPLETED
Double-Blind, Randomized, Single Dose Escalation Safety Study of Intraarticular Bone Morphogenic Protein (38A BMP-7) in Subjects With Osteoarthritis (OA) of the Knee PHASE1COMPLETED
Short-term Impact of Cyplexinol® on Self-reported Joint Pain nanCOMPLETED
Immediate Implants in Maxillary Premolar Region Using Xenograft vs Allograft nanUNKNOWN
Role of Novel Biomarkers Associated With In-stent Restenosis After Percutaneous Coronary Intervention nanUNKNOWN
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
Induce XT™ Bone Graft in Foot and Ankle Fusion nanENROLLING_BY_INVITATION
Genetic and Environmental Characteristics of Primary Pulmonary Hypertension nanCOMPLETED
Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response nanCOMPLETED
Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis nanNOT_YET_RECRUITING
Effect of BMPR-2 Gene Mutations on Hemodynamic Response by Iloprost Inhalation in Pulmonary Arterial Hypertension nanCOMPLETED
AO CSH Mainstream Study on Cervical Spine Degeneration nanNOT_YET_RECRUITING
Assessment of the TGF-beta Pathway and Micro-RNA in Pediatric Pulmonary Arterial Hypertension nanUNKNOWN
StratosPHere (Non-interventional Study) nanCOMPLETED
Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients nanUNKNOWN
Comparative Analysis of Gremlin-1, Syndecan-4 and IL-1 Beta Levels in Gingival Crevicular Fluid Among İndividuals With Periodontal Health and Stage III Periodontitis, Considering Both Smokers and Non-Smokers, Before and After Non-Surgical Periodontal Therapy nanACTIVE_NOT_RECRUITING
The Danish TURNER Cryopreservation Study nanRECRUITING
Osteogenic Profiling of Normal Calvarial Bone nanCOMPLETED
Osteogenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling nanCOMPLETED
Assessment of Guided Bone Regeneration in Atrophic Anterior Maxilla nanUNKNOWN
The OsteoStrand Plus Deformity Study nanUNKNOWN
Screening of Pulmonary Arterial Hypertension in BMPR2 Mutation Carriers nanCOMPLETED
Gremlin-1 and Wagner Classification: Potential Biomarker for Amputation in Diabetic Foot Patients nanCOMPLETED
Therapeutic Irrigation Procedures to Treat Apical Periodontitis nanCOMPLETED
Early Regenerative Intervention for Post-Traumatic Osteoarthritis nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a BMP1 binder may also engage these)

ProteinNameSimilarity
P98063 — 1.000 P98063 →
TLL2 Tolloid-like protein 2 1.000 landscape →
Q62381 — 1.000 Q62381 →
Q9WVM6 — 1.000 Q9WVM6 →
O57460 — 1.000 O57460 →
O57382 — 1.000 O57382 →
TLL1 Tolloid-like protein 1 1.000 landscape →
Q20176 — 0.999 Q20176 →
Q9DER7 — 0.994 Q9DER7 →
Q8JI28 — 0.993 Q8JI28 →
P98070 — 0.991 P98070 →
Q5R544 — 0.989 Q5R544 →
P25723 — 0.989 P25723 →
Q4R577 — 0.989 Q4R577 →
Q5R1W3 — 0.989 Q5R1W3 →
Q8CG16 — 0.987 Q8CG16 →
Q8CFG9 — 0.986 Q8CFG9 →
P56677 — 0.986 P56677 →
Q8CFG8 — 0.985 Q8CFG8 →
ST14 Suppressor of tumorigenicity 14 protein 0.985 landscape →
P98069 — 0.985 P98069 →
Q5G265 — 0.985 Q5G265 →
D5FM34 — 0.984 D5FM34 →
Q95220 — 0.984 Q95220 →
Q5G266 — 0.983 Q5G266 →
P53690 — 0.983 P53690 →
MMP14 Matrix metalloproteinase-14 0.983 landscape →
Q69DK8 — 0.983 Q69DK8 →
Q10739 — 0.982 Q10739 →
Q5G270 — 0.982 Q5G270 →