Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077524 | 0.94 | GCK (0.34) | GCKKCNH2 | |
| SCHEMBL1076404 | 0.80 | GCK (0.46) | GCKKCNH2 | |
| SCHEMBL1077799 | 0.77 | GCK (0.35) | GCKKCNH2 | |
| SCHEMBL1076088 | 0.77 | GCK (0.45) | GCK | |
| SCHEMBL1077237 | 0.73 | GCK (0.49) | GCKKCNH2 | |
| SCHEMBL1076346 | 0.72 | GCK (0.40) | GCK | |
| SCHEMBL1077525 | 0.71 | GCK (0.38) | GCKKCNH2 | |
| SCHEMBL1077267 | 0.70 | GCK (0.46) | GCKKCNH2 | |
| SCHEMBL1076033 | 0.70 | CFD (0.43) | GCK | |
| SCHEMBL1075816 | 0.69 | GCK (0.41) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276760-A1 | FUSED RING COMPOUNDS AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009125873-A1 | FUSED RING COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-15 | — | — | WO | disclosed |