SCHEMBL10778140

SCHEMBL10778140

O=C(O)CC(Cl)C(Cl)CC(=O)OC(=O)CC(Cl)C(Cl)CC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
GABRR1 P24046 2/20 0.32
LMNA P02545 2/20 0.32
TSHR P16473 2/20 0.30
FFAR3 O14843 1/20 0.30
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7820321 0.84 SLC22A6 (0.50) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL6519710 0.80 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL9060857 0.74 SLC22A6 (0.41) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL1868227 0.73
SCHEMBL9600868 0.72 SLC22A6 (0.68) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL7920481 0.72 SLC22A6 (0.39) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL25288454 0.70 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL5369808 0.70 FOLH1 (0.50) SLC22A6TDP1SMN1; SMN2TSHRFOLH1
SCHEMBL316476 0.70 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2FFAR3
SCHEMBL499437 0.70 TDP1 (0.70) SLC22A6TDP1SMN1; SMN2GABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0120411-B1 SCORCH-INHIBITED ELASTOMERIC COMPOSITION NIPPON ZEON CO., LTD. (JP) 1987-02-04 EP disclosed
US-4569958-A BLEND OF HALOGEN CONTAINING ELASTOMER, DI-OR TRI-THIOL-S-TRIAZINE,AND POLYCARBOXYLIC ACID NIPPON ZEON CO LTD (JP) 1986-02-11 US disclosed
EP-0120411-A1 Scorch-inhibited elastomeric composition NIPPON ZEON CO., LTD. (JP) 1984-10-03 EP disclosed