Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22221774 | 0.98 | L3MBTL1 (0.64) | L3MBTL1TSHRCACNA1BCYP2D6FAAH | |
| SCHEMBL2429378 | 0.93 | L3MBTL1 (0.66) | L3MBTL1CACNA1BCYP2D6FAAHPTGES | |
| SCHEMBL171811 | 0.88 | L3MBTL1 (0.68) | L3MBTL1FAAHPTGESALOX5PPARG | |
| SCHEMBL2091178 | 0.84 | L3MBTL1 (0.55) | L3MBTL1HTTUSP2LMNAALDH1A1 | |
| SCHEMBL9215275 | 0.84 | L3MBTL1 (0.55) | L3MBTL1PTGESALOX5PPARGPPARA | |
| SCHEMBL7774045 | 0.84 | L3MBTL1 (0.55) | L3MBTL1HTTUSP2LMNAALDH1A1 | |
| SCHEMBL2091175 | 0.84 | L3MBTL1 (0.55) | L3MBTL1HTTUSP2LMNAALDH1A1 | |
| SCHEMBL20267505 | 0.83 | L3MBTL1 (0.58) | L3MBTL1TSHRCACNA1BCYP2D6HTT | |
| SCHEMBL7199882 | 0.83 | L3MBTL1 (0.57) | L3MBTL1HTTUSP2LMNAALDH1A1 | |
| SCHEMBL4208924 | 0.82 | TSHR (0.76) | TSHRSMPD1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4648996-A | ANTIRHEUMATIC AGENTS, IMMUNOSUPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1987-03-10 | — | — | US | disclosed |