Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RHOA | P61586 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077872 | 1.00 | TSHR (0.52) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL9395446 | 0.87 | TSHR (0.48) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL9395434 | 0.87 | TSHR (0.48) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL8912587 | 0.85 | TSHR (0.44) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL7745837 | 0.85 | TSHR (0.34) | TSHR | |
| SCHEMBL11850207 | 0.83 | TSHR (0.43) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL7594167 | 0.83 | — | — | |
| SCHEMBL6050159 | 0.82 | TSHR (0.50) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL6050151 | 0.82 | TSHR (0.50) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL3795992 | 0.81 | TSHR (0.44) | TSHRTDP1SMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905511-B1 | Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions | INVISTA TECH SARL (CH) | 2013-03-27 | — | — | EP | claimed |
| CN-102639568-A | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORP | 2012-08-15 | — | — | CN | claimed |
| EP-2277623-A2 | Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2011-01-26 | — | — | EP | claimed |
| EP-1448298-B1 | POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS | INVISTA TECH SARL (CH) | 2010-09-22 | — | — | EP | claimed |
| EP-1586598-B1 | Process for preparation of polymeric, phosphorus-containing compositions | INVISTA TECH SARL (CH) | 2009-09-09 | — | — | EP | claimed |
| EP-1571172-B1 | Polymeric, phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA TECH SARL (CH) | 2008-10-22 | — | — | EP | claimed |
| EP-1534657-B1 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA TECH SARL (CH) | 2008-10-08 | — | — | EP | claimed |
| US-7388121-B2 | Process to separate butadiene dimers | DSM IP ASSETS B.V. (NL) | 2008-06-17 | — | — | US | claimed |
| EP-1905511-A2 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2008-04-02 | — | — | EP | claimed |
| EP-1448668-B1 | POLYMERIC, PHOSPHOROUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, ISOMERIZATION AND HYDROFORMYLATION REACTIONS | DU PONT (US) | 2006-08-09 | — | — | EP | claimed |
| EP-0543739-B1 | Process for the preparation of alkyl adipates | RHONE POULENC CHIMIE (FR) | 1996-01-31 | — | — | EP | claimed |
| WO-1995028228-A1 | BIDENTATE PHOSPHITE AND NICKEL CATALYST COMPOSITIONS FOR HYDROCYANATION OF MONOOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-10-26 | — | — | WO | claimed |
| WO-1995014659-A1 | PROCESSES AND CATALYST COMPOSITIONS FOR HYDROCYANATION OF MONOOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-06-01 | — | — | WO | claimed |
| WO-1995006027-A1 | PROCESS FOR THE PREPARATION OF A MIXTURE OF ALKYL PENTENOATES | DSM N.V. (NL) | 1995-03-02 | — | — | WO | claimed |
| EP-0177641-B1 | MANUFACTURE OF BUTANEDICARBOXYLIC ACID ESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-03 | — | — | EP | claimed |
| EP-0251728-B1 | CARBOALKOXYLATION OF BUTADIENE TO FORM DIALKYL ADIPATE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-29 | — | — | EP | claimed |
| EP-0251728-A2 | Carboalkoxylation of butadiene to form dialkyl adipate | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-07 | — | — | EP | claimed |
| US-4692549-A | Carboalkoxylation of butadiene to form dialkyl adipate | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-08 | — | — | US | claimed |
| US-4550195-A | CARBONYLATION OF BUTADIENE WITH CARBON MONOXIDE AND ALCOHOL | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-29 | — | — | US | claimed |
| EP-0025112-B1 | PROCESS FOR THE PREPARATION OF 3-PENTENOIC ACID ESTERS OF ALCANOLS CONTAINING 1 TO 4 CARBON ATOMS | BASF Aktiengesellschaft (DE) | 1982-04-07 | — | — | EP | claimed |