SCHEMBL6050159

SCHEMBL6050159

C=CCOC(=O)CC=CCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 2/20 0.36
NR1I2 O75469 1/20 0.36
PGR P06401 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
PTGS2 P35354 1/20 0.36
PDE4D Q08499 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
PKM P14618 1/20 0.35
MAPT P10636 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
ALDH1A1 P00352 6/20 0.34
HSD17B10 Q99714 4/20 0.34
ALOX15 P16050 1/20 0.34
GAA P10253 1/20 0.33
PTGS1 P23219 1/20 0.33
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6050151 1.00 TSHR (0.50) TSHRTDP1CYP3A4NR1I2PGR
SCHEMBL9395446 0.89 TSHR (0.48) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL9395434 0.89 TSHR (0.48) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL28263077 0.85 TSHR (0.51) TSHRTDP1CYP3A4NR1I2PGR
SCHEMBL10763073 0.82 TSHR (0.44) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL10763069 0.82 TSHR (0.44) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL9395439 0.82 ALDH1A1 (0.50) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL1077874 0.82 TSHR (0.52) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL1077872 0.82 TSHR (0.52) TSHRTDP1CYP3A4NPSR1SMN1; SMN2
SCHEMBL8912587 0.80 TSHR (0.44) TSHRTDP1NPSR1SMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001543-B Anti-impact modifier and polymer composition comprising it 罗门哈斯公司 2019-10-01 CN claimed
CN-107001543-A Anti-impact modifier and the polymer composition comprising it 罗门哈斯公司 2017-08-01 CN claimed
CN-105964196-A Composite ball containing self-assembly microcapsule and preparation method thereof 天津工业大学 2016-09-28 CN claimed
CN-107001543-B Anti-impact modifier and polymer composition comprising it 罗门哈斯公司 2019-10-01 CN disclosed
CN-109844640-A Self-emission type photosensitive resin composition, color filter and image display device manufactured using the same 东友精细化工有限公司 2019-06-04 CN disclosed
CN-109749678-A Glass fibre guard glass fibre cotton bonding agent 吴苹 2019-05-14 CN disclosed
CN-109627387-A Acrylate-styrene bipolymer-acrylonitrile core-shell graft copolymer preparation method 重庆云天化瀚恩新材料开发有限公司 2019-04-16 CN disclosed
CN-109514954-A Laminated body 株式会社可乐丽 2019-03-26 CN disclosed
CN-107112587-B Solid state secondary battery, solid electrolyte composition, battery electrode sheet 富士胶片株式会社 2019-03-19 CN disclosed
CN-105797660-B A kind of method that oil-soluble etherified amino resins prepare capsule 天津工业大学 2019-02-15 CN disclosed
CN-108289801-A Oral care gel 高露洁-棕榄公司 2018-07-17 CN disclosed
CN-101311215-A Organic protective film composition DONGJIN SEMICHEM CO LTD (KR) 2008-11-26 CN disclosed
CN-100383338-C Recyclable moisture proof packaging paper PT PABRIK KERTAS TJIVVI KIMIA (ID) 2008-04-23 CN disclosed
US-7019068-B2 Polymer compositions comprising telomers and articles or parts using these compositions SOLVAY (SOCIETE ANONYME) (BE) 2006-03-28 US disclosed
CN-1685109-A Recyclable moisture proof packaging paper PT PABRIK KERTAS TJIVVI KIMIA (ID) 2005-10-19 CN disclosed
EP-1368422-B1 POLYMER COMPOSITIONS COMPRISING TELOMERS AND ARTICLES OR PARTS USING THESE COMPOSITIONS SOLVAY (BE) 2005-08-24 EP disclosed
CN-1590457-A Curable composition and its use MITSUI CHEMICALS INC (JP) 2005-03-09 CN disclosed
US-20040097625-A1 Polymer compositions comprising telomers and articles or parts using these compositions SOLVAY (SOCIETE ANONYME) (BE) 2004-05-20 US disclosed
EP-1368422-A1 POLYMER COMPOSITIONS COMPRISING TELOMERS AND ARTICLES OR PARTS USING THESE COMPOSITIONS SOLVAY (SOCIETE ANONYME) (BE) 2003-12-10 EP disclosed
WO-2002057351-A1 POLYMER COMPOSITIONS COMPRISING TELOMERS AND ARTICLES OR PARTS USING THESE COMPOSITIONS Solvay (Société Anonyme) (BE) 2002-07-25 WO disclosed